109 citations
,
September 1999 in “Archives of Dermatology” Combining fluticasone propionate and UV-A is more effective for vitiligo than using either alone.
8 citations
,
March 2017 in “Journal of Cosmetic and Laser Therapy” Punch grafting treats vitiligo faster but can cause a cobblestone look, while follicular hair transplantation is slower but looks better and has no side effects.
September 2023 in “Journal of the American Academy of Dermatology” Spanish speakers with limited English search most for "pigmentation/dark spots."
2 citations
,
January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
59 citations
,
March 2003 in “The Lancet” Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
November 2024 in “Jurnal Biomedika dan Kesehatan” Premature graying in young children can affect self-esteem, and addressing underlying health issues may reverse it.
11 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
2 citations
,
April 2024 in “Cosmetics” Plant extracts can help remove permanent makeup without lasers.
1 citations
,
June 2025 in “Journal of Cellular and Molecular Medicine” Plant-derived compounds may help reverse grey hair by boosting melanin production.
5 citations
,
January 2015 in “Skin appendage disorders” Colored hair-thickening fibers can help hide hair loss in some people with Epidermolysis Bullosa but may cause scalp irritation.
Some alternative treatments for vitiligo show promise but need more research to confirm their safety and effectiveness.
46 citations
,
April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.
2 citations
,
May 2018 in “Dermatologic Surgery” Trichopigmentation is a non-invasive, reversible treatment for hair loss that offers natural-looking results for both men and women.
26 citations
,
December 2022 in “Molecules” Nanotechnology can improve treatments for skin discoloration.
Acitretin treatment unexpectedly darkened a patient's gray hair.
2 citations
,
December 2013 in “Journal of Cosmetic Dermatology” UV treatment can damage hair, so protection is advised.
12 citations
,
December 2017 in “Food and chemical toxicology” Permanent hair dye mixtures can irritate and damage the skin.
48 citations
,
March 1997 in “Seminars in Cutaneous Medicine and Surgery” Vitiligo causes white skin patches but can be treated in many ways.
August 2025 in “Journal of Cosmetic Dermatology” Topical treatments and lasers can improve axillary hyperpigmentation, but no best method is established yet.
21 citations
,
December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
February 2024 in “Journal of Cosmetic Dermatology” White hair patch repigmented and hair regrew in a balding patient after treatment with exosomes and laser.
July 2026 in “Current Issues in Molecular Biology” Plerixafor may help restore skin pigmentation safely.
10 citations
,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
15 citations
,
June 1993 in “Archives of Dermatology” A 22-year-old's gray hair partially turned back to its original color without known causes.
February 2022 in “Brazilian Journal of Health Review” Most cases were lichen planus pigmentosus, highlighting the need for accurate diagnosis for proper treatment.
9 citations
,
September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
6 citations
,
October 2006 Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.
17 citations
,
December 2013 in “Dermatologic Surgery” The treatment improved hair color in most vitiligo patients without major side effects.