April 2017 in “Journal of Dermatological Science” Certain flavonoids can improve the growth of pigmented hair in mice.
11 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
April 2024 in “Authorea (Authorea)” Stopping heptaminol medication reversed hair color loss in a patient on dialysis.
2 citations
,
January 2023 in “Dermatologic Therapy” CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.
20 citations
,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
26 citations
,
December 2022 in “Molecules” Nanotechnology can improve treatments for skin discoloration.
20 citations
,
February 2001 in “Dermatologic Surgery” Micropigmentation effectively hides scalp scars with few complications.
118 citations
,
January 1992 in “Experientia”
Acitretin treatment unexpectedly darkened a patient's gray hair.
17 citations
,
April 2002 in “Contact Dermatitis” Minoxidil 5% caused skin discoloration in a man using it for hair loss.
October 2024 in “Indian Journal of Dermatology” Early biopsy is crucial for diagnosing rare skin sarcoidosis, improving treatment.
73 citations
,
October 2003 in “Journal of Pharmacology and Experimental Therapeutics” Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
1 citations
,
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Increased PHGDH expression causes early melanin buildup in hair follicles.
15 citations
,
August 2014 in “Journal of dermatological science” Pueraria thunbergiana extract may help prevent hair from turning gray.
October 2025 in “Molecular Genetics and Genomics” 1 citations
,
February 2025 in “Photodermatology Photoimmunology & Photomedicine” 830 nm LED light effectively treats and prevents skin redness and dark spots, while 590 nm LED light only helps prevent them.
50 citations
,
February 2004 in “Journal of Investigative Dermatology” 31 citations
,
February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.
40 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
July 2025 in “Journal of Investigative Dermatology” Reducing PEDF may help treat hair loss.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
March 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” Vitiligo treatment requires a personalized mix of therapies to restore skin color and improve life quality.
2 citations
,
June 2024 in “Archives of Dermatological Research” Combining FCS and MPG is more effective for treating stable vitiligo than using either alone.
6 citations
,
January 2018 in “Advances in experimental medicine and biology” Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
1 citations
,
October 2019 in “International Journal of Dermatology and Venereology” Zebrafish help understand genetic causes of skin pigment disorders like albinism.
62 citations
,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
January 2024 in “Dermatologic therapy” Fire Needle Therapy may help bring back skin color in vitiligo by affecting cell growth signals.
7 citations
,
July 2016 in “Journal of Biomedical Materials Research Part A” cGEL hydrogel improves melanin production in skin cells, making it a promising option for skin treatments.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
January 2025 in “International Journal of Dermatology” Better diagnostic tools and treatment guidelines are needed for segmental vitiligo and related pigment issues.