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Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

Two impurities in finasteride were identified and characterized as cyclohexyl and phenyl analogs.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.

The fragrance cyclohexyl salicylate helps promote hair growth and increase hair stem cell numbers.

Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

Researchers made two new compounds that could be used for medicine.

The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

The study successfully identified the structure of finasteride.

A new method to make Finasteride is more cost-effective and yields 16%.

The chitosan/PDRN polyplex improved wound healing in diabetic rats.

PPAR β/δ is important for skin health and disease treatment, but more research is needed.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

The protein AtRXR3 limits root hair growth in Arabidopsis, affecting phosphorus uptake.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.

Potential new drugs for treating PCOS were identified.

Peperomia pellucida shows promise for developing new therapeutic drugs.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.