research Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.
Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
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600-630 / 1000+ resultsresearch Targeting of Smoothened for therapeutic gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles
HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.
research Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes
Interleukin-1 increases keratin K6 production in skin cells.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research Switching roles: the functional plasticity of adult tissue stem cells
Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
research Application of microneedle patches for drug delivery; doorstep to novel therapies
Microneedle patches could replace injections but need more development for better use in medicine.
research A Review of Edible Jujube, the Ziziphus jujuba Fruit: A Heath Food Supplement for Anemia Prevalence
Jujube fruit may help prevent anemia by boosting blood production.
research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
ASC-CM is more effective than EV for treating osteoarthritis.
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals
EGFR signaling is essential for ear cell regeneration in both birds and mammals.
research NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium
NFAT5 triggers atherosclerosis under stress by activating inflammation in blood vessels.
research Functional Food Nutrients, Redox Resilience Signaling and Neurosteroids for Brain Health
Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
research Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments
THSG from a Chinese plant helps with aging and related diseases.
research Endogenous steroid hormones in hair: Investigations on different hair types, pigmentation effects and correlation to nails
Body hair isn't a good substitute for scalp hair in steroid analysis.
research Natural Sources of Therapeutic Agents Used in Skin Conditions
Bee venom, fig, and geranium oil can effectively treat skin conditions and are safer alternatives to some conventional drugs.
research Fibroblasts in Diabetic Foot Ulcers
Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
research In vivo CD44‐CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance
The CD44-CD49d complex boosts T cell activation and survival in autoimmune disease.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research A systematic summary of survival and death signalling during the life of hair follicle stem cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.
research The role of WNT10B in physiology and disease: A 10-year update
WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
research Liposomes and Other Nanocarriers for the Treatment of Acne Vulgaris: Improved Therapeutic Efficacy and Skin Tolerability
Nanocarriers can make acne treatments more effective and gentle on the skin.
research MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research The impact of VDR expression and regulation in vivo
VDR regulation varies by tissue and is crucial for its biological functions.
research Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase
Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.
research Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research Colchicine in Managing Skin Conditions: A Systematic Review
Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.