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The review discusses the potential of Semecarpus anacardium, an Ayurvedic plant, in promoting hair growth due to its bioactive compounds like anacardic acid, biflavonoids, and phenolic compounds. These compounds have antioxidant, anti-inflammatory, and antimicrobial properties that protect hair follicles and enhance follicular cycling. The plant influences key signaling pathways important for follicle regeneration. However, raw preparations can be toxic, highlighting the need for detoxification and safe formulation. Current evidence is mainly from in vitro and animal studies, with limited human trials, indicating a need for further research on extraction methods, delivery systems, and clinical evaluations to confirm its efficacy and safety in humans.

This review explores the advancements in polysaccharide-based niosomes as drug delivery systems, emphasizing their versatility and potential in various biomedical applications. Niosomes offer benefits such as improved chemical stability, cost-effectiveness, and enhanced drug delivery across ocular, oral, nose-to-brain, pulmonary, cardiac, and transdermal routes. They are particularly effective in cancer therapy, enabling precise drug release at tumor sites, and in reducing cardiotoxicity. Polysaccharides enhance niosomes' biocompatibility, biodegradability, and antibacterial properties, making them superior to other polymers. The review also highlights specialized niosome types like polyhedral niosomes, proniosomes, and elastic niosomes, each offering unique advantages in drug delivery. Despite their potential, challenges such as manufacturing scalability and stability need addressing for clinical translation. Future research directions include integrating stimuli-responsive materials and conducting clinical studies for personalized therapy.