4 citations
,
August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
December 2025 in “Neurobiology of Stress” People who recently attempted suicide during depression showed signs of adrenal fatigue, but had higher DHEA levels around the attempt time.
16 citations
,
January 2014 in “Obesity surgery” Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
380 citations
,
February 2023 in “Journal of Clinical Medicine” PCOS is influenced by various factors and may be managed by restoring gut health and using new therapies.
219 citations
,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
175 citations
,
January 2020 in “European Journal of Endocrinology” Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
138 citations
,
June 2023 in “Molecules” Skin pigmentation varies due to genetics, UV exposure, and drugs, with treatments available but requiring medical advice.
119 citations
,
June 2021 in “Heliyon” Licorice has many health benefits but should be used carefully due to possible side effects.
106 citations
,
January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
102 citations
,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
90 citations
,
July 2014 in “Conservation Physiology” Hair cortisol levels in brown bears can be affected by both long-term and short-term stress.
55 citations
,
August 2003 in “Ultrasound in Obstetrics and Gynecology” Ultrasound and color Doppler can help diagnose and decide treatment for early puberty in young girls.
45 citations
,
November 2024 in “International Journal of Molecular Sciences” Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
44 citations
,
September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
44 citations
,
November 2018 in “Journal of applied ecology” Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.
22 citations
,
May 2019 in “Animals” High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.
16 citations
,
March 2025 in “International Journal of Molecular Sciences” Extracellular vesicles show promise in skin treatments but need more research and standardization.
16 citations
,
January 2021 in “Frontiers in veterinary science” Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.
15 citations
,
January 2020 in “Experimental Dermatology” The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.
14 citations
,
April 2022 in “Climacteric” Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
12 citations
,
January 2018 in “Journal of Clinical Laboratory Analysis” Certain IL-18 gene variations may increase the risk of alopecia areata.
12 citations
,
April 2017 in “Experimental and Therapeutic Medicine” Patients with severe active alopecia areata have lower CD200 expression and an imbalance in their immune system.
10 citations
,
November 2024 in “Diagnostics” High androgen levels cause skin issues in PCOS, affecting quality of life.
10 citations
,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
10 citations
,
September 2019 in “Frontiers in Veterinary Science” Older steers have higher hair cortisol levels than younger steers.
9 citations
,
February 2023 in “Medicine” Traditional Chinese medicine may help relieve symptoms of Cronkhite-Canada syndrome.
8 citations
,
November 2024 in “Journal of Neuroendocrinology” Gut bacteria affect steroid levels, influencing health conditions and potential treatments.
7 citations
,
August 2025 in “European Journal of Endocrinology” Long-term use of calcineurin inhibitors in transplant patients can cause hormone issues that can be managed with proper care.
4 citations
,
October 2022 in “Genes” Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.
4 citations
,
August 2021 in “Frontiers in Cell and Developmental Biology” Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.