August 2024 in “Quality in Sport” PRP helps with skin, hair, and wound treatments but needs more research for standard use.
December 2020 in “Journal of Aesthetic Nursing” Injecting platelet-rich plasma into the scalp stimulates hair growth, increases hair density, and treats hair loss effectively with minimal side effects.
October 2020 in “Journal of Aesthetic Nursing” Platelet-rich plasma (PRP) injections effectively treat hair loss and thinning in both men and women, with high satisfaction and no major side effects.
March 2019 in “European archives of medical research” Platelet-rich plasma injections are a cheap and effective way to reduce hair loss and improve hair quality in people with mild to moderate androgenetic alopecia.
January 2022 in “Revista del Centro Dermatológico Pascua” PRP therapy is a promising treatment for male hair loss on the vertex.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
4 citations
,
March 2018 in “PloS one” Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.
September 2019 in “Journal of Investigative Dermatology” Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.
August 2019 in “Journal of The American Academy of Dermatology” No link found between hair loss severity and PSA levels in men.
6 citations
,
May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
July 2021 in “Archives of Dermatological Research” Alopecia patients have less GPER-1, which might affect hair loss.
20 citations
,
June 2015 in “Hormone Molecular Biology and Clinical Investigation” Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
2 citations
,
January 1994 in “Yakubutsu dōtai” Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.
93 citations
,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
33 citations
,
November 2008 in “European Journal of Pharmaceutical Sciences” St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
118 citations
,
September 2004 in “Clinics in Dermatology” Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.
8 citations
,
April 2020 in “Facial Plastic Surgery Clinics of North America” Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.
20 citations
,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
3 citations
,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
137 citations
,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
104 citations
,
March 2014 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” DHT may increase the risk of heart disease and death in elderly men.
35 citations
,
February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
35 citations
,
May 1986 in “Clinics in endocrinology and metabolism” The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
32 citations
,
August 1999 in “Journal of Investigative Dermatology” Early onset hair loss linked to genetics and androgen levels.
11 citations
,
May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
3 citations
,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
7 citations
,
January 2022 in “Animal Reproduction” Using rodents for research shows that health problems in the womb can cause diseases later in life.
75 citations
,
June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
46 citations
,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
39 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.