research Patient‐Level Adverse Event Patterns in a Single‐Institution Study of the Multi‐Kinase Inhibitor Sorafenib
Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.
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780-810 / 1000+ resultsresearch Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States
Microvascular damage and platelet issues persist in ulcerative colitis remission, helping assess disease states.
research The Enterobacter sp. SA187 stimulates stress-responsive genes and promotes salt and heat stress tolerance in tomato plants
Enterobacter sp. SA187 helps tomato plants grow better in salt and heat by boosting stress-related responses.
research Whole-Genome Resequencing Reveals Selection Signal Related to Sheep Wool Fineness
Genes linked to wool fineness in sheep have been identified.
research Somatotropin Penetration Testing from Formulations Applied Topically to the Skin
The new topical growth hormone formula has high skin penetration and bioavailability.
research Unveiling a Shared Precursor Condition for Acne Keloidalis Nuchae and Primary Cicatricial Alopecias
A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.
research Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction
Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.
research A rash diagnosis
The man's rash, hair loss, and vision issues were due to syphilis, not CMV.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Long and short non-coding RNA and radiation response: a review
Non-coding RNAs could help detect and treat radiation damage.
research Malnutrition and Allergies: Tipping the Immune Balance towards Health
Proper nutrition can help balance the immune system and reduce allergies.
research Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse
Reduced plakoglobin and steroid abuse increase the risk of heart rhythm issues.
research Adrenocortical Adenocarcinoma in a Syrian Golden Hamster ( Mesocricetus auratus) With Suspected Hyperadrenocorticism
Adrenal tumors in hamsters are rare and hard to diagnose, highlighting the need for better diagnostic tools.
research Does creatine cause hair loss? A 12-week randomized controlled trial
Creatine does not cause hair loss.
research Highlights from the Literature
Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
research Association Between ACE I/D Gene Polymorphism and Dyslipidemia in Hypertensive Patients with Ischemic Heart Disease Complication Among Ethiopian Population
Certain genes and high cholesterol levels increase heart disease risk in Ethiopian patients with high blood pressure.
research Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome
Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
research Molecular characterization of GhPLDα1 and its relationship with secondary cell wall thickening in cotton fibers
GhPLDα1 helps thicken cotton fiber walls by boosting cellulose production.
research Empirical evidence of observer bias in randomized clinical trials: updated and expanded analysis of trials with both blinded and non-blinded outcome assessors
Non-blinded assessors tend to overestimate effects in trials by about 29%.
research Long-acting microneedle formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability
Compound 6 is a promising candidate for better wound healing.
research Expanding the Scope of PROTACs: Opportunities and Challenges in Topical Delivery
Topical PROTACs show promise for treating skin conditions but need better stability and delivery methods.
research Impact of a High-Fat High-Carbohydrate (HFHC) Diet at a Young Age on Steroid Hormone Hair Concentrations in Mice: A Comparison with a Control Diet and Nutraceutical Supplementation
A balanced diet is crucial for normalizing hormone levels and managing obesity-related issues.
research Alopecia Areata Is Associated with an Increased Risk for Prediabetes and Obesity: A Nationwide Case—Control Study
People with Alopecia Areata are more likely to have prediabetes and obesity.
research Titanium dioxide nanoparticles: a promising candidate for wound healing applications
Titanium dioxide nanoparticles can help heal wounds faster and better.
research Short-term cryoprotectant-free cryopreservation at −20°C does not affect the viability and regenerative capacity of nanofat
Storing nanofat at -20°C for 7 days does not harm its ability to regenerate.
research Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway
17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
research Diagnosis, Pathogenesis and Management of Polycystic Ovary Syndrome
Lifestyle changes and insulin-sensitizing drugs are effective for managing PCOS.
research Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes
CRH promotes fat production in skin cells, affecting conditions like acne.