research Myeloproliferative disorder associated with alopecia universalis
Ruxolitinib helped regrow hair in a woman with a blood disorder and complete hair loss.
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research A Retrospective Evaluation of the Laboratory Findings of Dermatology Patients Whose Biotin Levels Were Checked
Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research Irisin promotes hair growth and hair cycle transition by activating the GSK ‐3β/β‐catenin pathway
Irisin can promote hair growth by activating a specific signaling pathway.
research Signal Peptide-CUB-EGF-like Domain-Containing Protein 3 (SCUBE3): From Molecule to Therapy
SCUBE3 is a potential target for cancer and alopecia treatment but is challenging to target due to its varied roles.
research Faculty Opinions recommendation of A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia.
Dutasteride 0.5mg was found to be more effective than finasteride 1mg in treating male pattern hair loss, with similar side effects.
research Megaloblastic Anemia in a Patient on Peritoneal Dialysis Returning from Kenya
Proguanil can cause anemia and hair loss in kidney disease patients.
research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research British Association of Dermatologists living guideline for managing people with alopecia areata 2024
The guideline provides recommendations for managing alopecia areata effectively.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Nanomedicine-based immunotherapy for tissue regeneration
Nanomedicine-based immunotherapy shows promise in improving tissue repair and regeneration.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research The correlation between corona virus disease 2019 and alopecia areata: a literature review
COVID-19 can increase the risk of hair loss, especially in people over 40.
research Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications
Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.
research A retrospective analysis of disease epidemiology, comorbidities, treatment patterns, and healthcare resource utilization of alopecia areata in the United Arab Emirates using claims database
Alopecia areata in Dubai mostly affects men, often involves autoimmune disorders, and has high healthcare costs, especially for psychological issues.
research Molecular Mechanisms of Hair Follicle Development
Understanding hair follicle development helps create treatments for hair loss and improve hair health.
research Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis
Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
research Identifying barriers and disparities in the healthcare of patients with alopecia areata: a mixed-methods analysis using claims data and qualitative interview data
Patients with alopecia areata face treatment barriers due to lack of reimbursement and need more support and information.
research Fractionated CO2 Laser in Combination with Topical Tacrolimus for Chronic Alopecia Areata: A Case Series Study
Combining fractionated CO2 laser with tacrolimus may help treat chronic alopecia areata.
research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
PBMCsec can help reduce and improve thick skin scars.
research Exosomes as Regenerative Therapeutics in Non-Scarring Alopecia: Current Perspectives and Future Directions
Exosome therapy shows promise for treating hair loss but needs more research and standardization.
research Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars
New drug delivery systems show promise in effectively treating pathological scars.
research Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses
Targeting protein S-palmitoylation could lead to new skin disease treatments.
research Comparison of Current International Guidelines for the Management of Alopecia Areata—Comprehensive Review
International guidelines for treating alopecia areata vary, focusing on different treatment options and related health issues.
research Research Progress on the Molecular Mechanism of Poultry Feather Follicle Development
Key pathways like WNT, EGF, FGF, SHH, and BMP regulate poultry feather growth, with BMP inhibiting it.
research Alopecia areata: recognition, diagnosis and management
Alopecia areata causes patchy hair loss due to the immune system attacking hair follicles.
research Prescribing patterns amongst UK dermatologists for the treatment of alopecia areata, female pattern hair loss, and frontal fibrosing alopecia
UK dermatologists commonly use corticosteroids and minoxidil to treat hair loss conditions.
research How to treat androgenetic alopecia – the most common form of hair loss. A review
Androgenetic alopecia can be treated with minoxidil and finasteride, requiring long-term use and patient cooperation.