research Simultaneous Estimation of Finasteride and Tamsulosin Hydrochloride in Combined Dosage Forms by RP-HPLC-PDA Method
The method accurately measures Tamsulosin and Finasteride in medication and is suitable for regular quality checks.
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60-90 / 1000+ results research Mitochondrial Oxygen Consumption and Immunocytochemistry of Human Dental Pulp Stem Cell Following 808 nm PBM Therapy: A 3D Cell Culture Study
PBM therapy improves mitochondrial function and promotes tissue regeneration in dental pulp stem cells.
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research PRAME Expression in Mammary and Extramammary Paget Disease
PRAME is often present in Paget disease and could help in diagnosis, but more research is needed.
research Depletion of Gsdma1/2/3 alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway
Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Biocompatible exosomes derived from Pinctada martensii mucus for therapeutic melanin regulation via α-MSH/NF-κB/MITF pathway
Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
research Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths
PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
research Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
Blocking progesterone metabolism can cause depression-like behavior in mice.
research Evidence-based consensus on the clinical application of photobiomodulation
A panel of 21 experts developed a consensus on the clinical application of photobiomodulation (PBM), concluding it is a safe and effective treatment for conditions like peripheral neuropathy, androgenic alopecia, wound ulcers, diabetic foot ulcer pain, and acute radiation dermatitis. Red light PBM does not cause DNA damage, supporting its safety for adults. The guidelines are intended to help clinicians use PBM safely and effectively, with future research anticipated to improve understanding of this noninvasive technique.
research The comparison of the mesenchymal progenitor cell coating state on the MBA and DBM as the biochemical scaffolds
The demineralized bone matrix scaffold is better for cell attachment than the mineralized bone allograft.
research 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways
Particulate matter causes inflammation in hair cells, potentially harming hair growth.
research Patient prioritisation of items to develop the Patient‐Reported Impact of Dermatological Diseases measure: A global Delphi study
The study created a 27-item measure to assess the impact of skin diseases.
research Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.
Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
research 3D-printed porous functional composite scaffolds with polydopamine decoration for bone regeneration
The scaffold with polydopamine and bioactive glass effectively promotes bone regeneration.
research Effect of Compound Diandao Pulvis Drug Facial Mask on Acne Model of Rabbit's Ears
CDPDFM can improve acne symptoms in rabbit ears.
research Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice
Dutasteride may protect the brain in early Parkinson's disease.
research Finasteride Attenuates Pathological Gambling in Patients With Parkinson Disease
Finasteride reduces gambling symptoms in Parkinson's patients.
research Influence of age and of testosterone on the response of male rats to parachlorophenylalanine
PCPA induces hypersexual behavior in male rats regardless of age or castration status.
research Deposition of 18-MEA onto Damaged Hair to Form a Persistent Hydrophobicity
18-MEA and SPDA can restore damaged hair's smoothness and reduce frizz.
research Poster abstract: Novel dissolving microarray patches for intradermal delivery of finasteride
Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.
research Three months extended-release microspheres prepared by multi-microchannel microfluidics in beagle dog models
A new device, IVL-PPF Microsphere®, was created to deliver a hair loss drug for up to 3 months with one injection, potentially replacing daily pills.
research Poly‑D,L‑lactic acid (PDLLA) scalp microinjection protocol with optional light microneedling priming for non‑scarring alopecia: A prospective pilot case series
This pilot case series investigated the effects of Poly-D,L-lactic acid (PDLLA) scalp microinjections on 20 patients with non-scarring alopecia, finding that 90% showed hair regrowth improvement by week 12, with results sustained at week 24. Optional microneedling was used in 14 patients to enhance PDLLA distribution. No serious adverse events were reported, suggesting good short-term tolerability. However, the study's preliminary findings are limited by its small sample size, lack of a control group, and subjective endpoints, indicating a need for further research with objective measures and extended follow-up to confirm PDLLA's efficacy and safety in hair regeneration.
research pMB FLASH - Status and Perspectives of Combining Proton Minibeam with FLASH Radiotherapy
Combining Proton Minibeam with FLASH Radiotherapy may improve cancer treatment by reducing side effects and increasing effectiveness.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
research Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
Dissolving microneedle patches can effectively deliver drugs over time.
research Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle
The new micelle formulation delivers acne treatment more effectively and safely than current gels.
research Mitogen‐regulated protein/proliferin mRNA induction following single applications of tumor promoters to murine skin
mrp/plf-mRNA can indicate tumor-promoting effects in skin.
research In-vivo Assessment of Neuropharmacological Activity of Methanol Bark Extract of Mimosa Pudica in Mice
Mimosa pudica extract may help create new sedative and anti-anxiety drugs.