research Dissolving microneedles: an advanced approach for transdermal drug delivery
Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.
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150-180 / 1000+ results research In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
research Lyophilized growth factor intralesional injection in female pattern hair loss: A clinical and trichoscopic study
Injections improve hair growth, density, and thickness in women safely.
research Description of the Intrafollicular Delivery of Large Molecular Weight Molecules to Follicles of Human Scalp Skin In Vitro
Properly formulated large molecules can reach active levels at the hair bulb.
research Evaluation of noninvasive biospecimens for transcriptome studies
Hair follicles and urine cell pellets are promising for transcriptome studies.
research Microneedles as a perspective for transdermal therapeutic systems
Microneedles could make it easier and less painful to deliver more types of drugs through the skin.
research COMPARATIVE STUDY BETWEEN INTRALESIONAL INJECTION OF PLATELET RICH PLASMA AND INTRA LESIONAL TRIAMCINOLONE FOR THE TREATMENT OF ALOPECIA AREATA
Steroid injections are more effective than platelet rich plasma for treating patchy hair loss.
research Dissolving microneedles: Applications and growing therapeutic potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research 267 Single- and multiple-ascending dose studies of DS-2325a, a KLK5 inhibitor for the treatment of Netherton syndrome
DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.
research Advancements in transdermal drug delivery using microneedles: technological and material perspective
Microneedle patches offer painless, effective drug delivery and are suitable for all ages.
research Treatment of Cystathionine β-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector
MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
research Gene Delivery to the Hair Follicle
Gene therapy shows promise for treating hair loss by targeting hair follicles.
research LB1139 AMP-303 injectable treatment for androgenetic alopecia: A multicenter, randomized, placebo-controlled feasibility study of a novel polysaccharide
AMP-303 safely increases hair growth in men with hair loss.
research Matrix-free cryo-microneedles array patch for 3D hair follicle organoids delivery and rapid hair regeneration
research Emerging smart microneedle technologies in psoriasis: convergence of nanocarriers, machine learning, and personalized delivery
Smart microneedles using advanced tech could improve psoriasis treatment.
research Adjuvant Therapy for Revision Rhinoplasty of Contracted Nose Using Polydeoxyribonucleotide and Invasive Bipolar Radiofrequency
Using PDRN injections and RF treatments improved revision nose surgery results without major side effects.
research Research Progress of Extracellular Vesicles-Loaded Microneedle Technology
Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
research Microneedles as transdermal drug delivery system for enhancing skin disease treatment
Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
research Hydrogel-Forming Microneedles for Transdermal Drug Delivery
Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
research Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research P113 Therapeutic efficacy of 1,927-nm fractionated thulium laser and polydeoxyribonucleotide on pattern hair loss
The thulium laser and PDRN injections effectively improved hair thickness in patients with pattern hair loss.
research Bullous Lesions at Polyethylene Glycol Interferon-alpha-2a Inoculation Site in a Hepatitis C Virus-infected Subject
A patient developed a blister at the injection site after hepatitis C treatment.
research Platelet-rich plasma for androgenetic alopecia: intradermal injection or microneedle delivery?
Microneedle delivery of platelet-rich plasma may be slightly better for hair regrowth than intradermal injection.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research Clinical efficacy of polyglutamate via microneedle delivery: a novel non-invasive therapy for androgenetic alopecia
Microneedle-delivered polyglutamate effectively and safely improves hair growth in androgenetic alopecia.
research 032 A multicomponent skin-targeted COVID-19 vaccine elicits robust humoral and cellular immune responses
The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.
research Acute inflammatory demyelinating polyneuropathy associated with pegylated interferon α 2a therapy for chronic hepatitis C virus infection
Pegylated interferon-alpha 2a can cause a rare nerve disorder, but early treatment can lead to full recovery.
research Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing
Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
research Development of a new therapeutic approach based on peptide nanoparticles delivering CRISPR-Cas9 for the specific targeting of KRAS mutations
Peptide nanoparticles can effectively deliver CRISPR-Cas9 to target KRAS mutations in cancer.
research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.