research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
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720-750 / 1000+ results research Pharmacodynamics and pharmacokinetics of P-3074, a new finasteride topical solution, administered at four different doses
P-3074 effectively blocks scalp DHT better than oral finasteride.
research Development of Pneumatic Dual-Cell Stacking Implanter
The new device can implant cell mixtures more effectively for hair loss treatment and is easier for operators to use.
research Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing
The new nanofiber patch speeds up diabetic wound healing and improves healing quality.
research Quality evaluation of the Finasteride polymorphic forms I and II in capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Sugar Surfactant‐Based Shampoos
Shampoos with sugar-derived surfactants clean hair well and are gentler than those with SLES.
research Hair keratin film as a substitute device for human hair
Keratin film can effectively replace human hair for testing hair damage.
research [Electrophoretic studies of acid mucopolysaccharides in skin, prekeratin of hair follicles and in keratoses of wool].
Chondroitin sulphate is more abundant than hyaluronic acid in skin and hair samples, except in gamma-keratosis.
research Fabrication and in vitro evaluation of silk fibroin-folic acid decorated paclitaxel and hydroxyurea nanostructured lipid carriers for targeting ovarian cancer cells: A double sword approach
The new drug carriers show promise for better targeting and treating ovarian cancer.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research Cosmetics and Cosmeceutical Applications of Chitin, Chitosan and Their Derivatives
Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
research Hydrogel-Forming Microneedles for Transdermal Drug Delivery
Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research UV light may induce hypertrichosis through production of PGE2
UV light might cause excessive hair growth by increasing PGE2 in the skin.
research Immunomodulatory Potential and Biocompatibility of Chitosan–Hydroxyapatite Biocomposites for Tissue Engineering
Chitosan–hydroxyapatite biocomposites are promising for tissue engineering due to their safety and ability to support healing.
research Encapsulation of curcumin into nanoparticles
Encapsulating curcumin in nanoparticles improves its stability, release, and absorption in the body.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Further errors in polymorph identification: furosemide and finasteride
Errors found in identifying furosemide and finasteride polymorphs due to incomplete data.
research Preparation of scaffolds from human hair proteins for tissue-engineering applications
Human hair proteins can be used to create scaffolds that support cell growth for tissue engineering.
research Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model
Platelet-rich plasma improves bladder function and reduces overactivity in ketamine-induced bladder issues.
research Drug conjugates crosslinked bioresponsive hydrogel for combination therapy of diabetic wound.
The hydrogel significantly improves healing in diabetic wounds.
research Evaluation of changes in skin biophysical parameters and appearance after pneumatic injections of non-cross-linked hyaluronic acid in the face
Injecting non-cross-linked hyaluronic acid into the face improved skin hydration, texture, pores, and reduced wrinkles.
research A New Strategy for Consumption of Functional Lipids from Ericerus pela (Chavannes): Study on Microcapsules and Effervescent Tablets Containing Insect Wax–Derived Policosanol
Microcapsules and effervescent tablets make insect lipids easier to consume.
research Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles For Effective Preservation And Delivery Of Fermented Herbal Extract For Enlarging Hair Bulb And Enhancing Hair Growth
The nanoparticles effectively deliver herbal extract to enhance hair growth.
research Altered Skin Permeation of Finasteride Using Clove Oil, Urea, and Lyophilized Powder of Grape Seed Extract
Clove oil and grape seed extract increase finasteride skin absorption, while urea decreases it.
research Injectable self-healing ceria-based nanocomposite hydrogel with ROS-scavenging activity for skin wound repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research New approach to 3-oxo-4-aza-5α-androst-1-ene-17β-(--butylcarboxamide)
A new method was developed to make finasteride for treating hair loss.
research Intravesical instillation of platelet-rich plasma for treatment of interstitial cystitis/bladder pain syndrome: A pilot study
Platelet-rich plasma shows promise in reducing pain for bladder pain syndrome.
research Antibacterial and wound healing stimulant nanofibrous dressing consisting of soluplus and soy protein isolate loaded with mupirocin
The new wound dressing speeds up healing and kills bacteria effectively.