68 citations
,
November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
55 citations
,
November 2018 in “American journal of human genetics” Mutations in the LSS gene cause a rare type of hereditary hair loss.
42 citations
,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
29 citations
,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
24 citations
,
January 2019 in “Biomaterials Science” The shape of fibrous scaffolds can improve how stem cells help heal skin.
22 citations
,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
16 citations
,
July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
15 citations
,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
4 citations
,
January 2019 in “Therapeutic Advances in Endocrinology and Metabolism” Medications for PCOS don't seem to raise heart disease risk.
2 citations
,
January 2016 in “Springer eBooks” Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
1 citations
,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
January 2025 in “International Journal for Research Trends and Innovation” PCOS management benefits from combining traditional herbs, modern medicine, and lifestyle changes.
May 2026 in “Frontiers in Cell and Developmental Biology” Collagen networks play a key role in hair loss and follicle miniaturization.
Deucravacitinib improves symptoms and reduces inflammation in Lichen Planopilaris.
Azelaic acid helps with skin pigmentation issues, but its full effects are not completely understood.
Ion sequential therapy improves heart function after a heart attack.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
117 citations
,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
78 citations
,
June 2021 in “Dermatology and Therapy” Future acne treatments should aggressively target inflammation to prevent scarring.
67 citations
,
August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
30 citations
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April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
28 citations
,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
January 2025 in “Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)” Oxidized LDL reduces cell growth but affects stem cell differentiation less negatively than cytokine-induced inflammation.
47 citations
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October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
27 citations
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July 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
22 citations
,
January 2018 in “Experimental Dermatology” The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.