42 citations
,
January 2006 in “Obstetrical & Gynecological Survey” The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
23 citations
,
May 2019 in “Expert Opinion on Therapeutic Patents” New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
March 2023 in “Biomedicine & Pharmacotherapy” GPR40 agonists help hair growth through the protein ANGPTL4.
31 citations
,
October 2010 in “Progress in lipid research” LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
April 2026 in “Frontiers in Cell and Developmental Biology” GPCRs are vital for wound healing by affecting cell growth and immune response.
March 2026 in “Brazilian Journal of Animal and Environmental Research” Deslorelin can help control reproduction and improve hair growth in German Spitz dogs.
February 2026 in “Editora Pasteur eBooks” A comprehensive, personalized approach is needed for treating female pattern hair loss and obesity, involving multiple medical disciplines and lifestyle changes.
4 citations
,
January 2019 in “Therapeutic Advances in Endocrinology and Metabolism” Medications for PCOS don't seem to raise heart disease risk.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
10 citations
,
November 2022 in “Protein & Cell” Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
March 2026 in “Anti-Aging Eastern Europe” PCOS treatment should be personalized based on individual symptoms and health goals.
November 2017 in “Dermatologic Therapy” A new topical solution safely reduces hair shedding by 38% on average by tightening a muscle in the scalp.
February 2025 in “Journal of Neonatal Surgery” Combining antidiabetic drugs, hormonal therapies, and lifestyle changes can improve health in women with PCOS.
4 citations
,
September 2025 in “Biomolecules” The effect of GLP-1 RAs on erectile function is unclear and needs more research.
17 citations
,
February 2018 in “Journal of Investigative Dermatology” PPAR-γ signaling improves mitochondrial function in hair follicles, potentially affecting hair growth and aging.
May 2023 in “Journal of Endocrinology and Reproduction” Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.
12 citations
,
November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
3 citations
,
June 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The conclusion suggests that focusing on certain cellular pathways may improve the prevention and repair of hair loss caused by radiotherapy.
2 citations
,
July 2022 in “Frontiers in Medicine” The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
January 2026 in “Biomedicines” Dysregulated lipid metabolism may play a role in male pattern baldness.
September 2023 in “Frontiers in Medicine” The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.
466 citations
,
June 2009 in “Experimental dermatology” We now understand more about what causes acne and this could lead to better, more personalized treatments.
219 citations
,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
62 citations
,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
6 citations
,
May 2020 in “Nutrients” Eating fewer calories may slow skin aging and improve skin health through various biological changes.
6 citations
,
October 2014 in “Experimental Dermatology” Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
4 citations
,
December 2024 in “European Journal of Medicinal Chemistry” New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
April 2024 in “Applied biological chemistry” Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
2 citations
,
December 2022 in “Journal of Clinical Medicine” Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
1 citations
,
October 2025 in “Journal of Personalized Medicine” Weight loss improves PCOS symptoms and overall health.