research The Role of Entrepreneurial Leadership and Innovation in the Future of Therapeutic Dermatology
Entrepreneurial companies are key to advancing dermatology treatments and patient care.
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research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research 1419 Pre-clinical in-vitro assays for high throughput screening of drug candidates for protection and restoration of immune privilege in alopecia areata
The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models
New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
research Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research
Hair organoids are effective for testing hair loss treatments.
research 080 Mouse models of alopecia areata: C3H/HeJ mice versus the humanized AA mouse model
The humanized AA mouse model is better for testing new alopecia areata treatments.
research Efficient Gene Editing for Heart Disease via ELIP-Based CRISPR Delivery System
ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.
research Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis
CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.
research The microfollicle: a model of the human hair follicle for in vitro studies
Microfollicles can effectively model human hair follicles for research and testing.
research Exploring the Chorioallantoic Membrane (CAM) as a Platform for Burn Wound Modelling and Analysis
The CAM is a useful model for studying burn wounds and testing treatments.
research 3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa
Scientists created a 3D skin model to study a chronic skin disease and test treatments.
research Keratin biomaterials for wound healing and tissue regeneration: A promising approach in biomedical applications
Keratin biomaterials could help heal wounds and regenerate tissue, but more testing is needed.
research Human hair follicle organ culture: theory, application and perspectives
Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
research Exosomes
Exosome therapies could help with skin and hair issues, but more testing is needed.
research Egyptian Traditional Herbal Medicine Candidate Adiantum Capillus-Veneris Linn. as a Symptomatic Treatment for COVID-19: A Review of its Mechanisms, Pros and Cons.
Maidenhair fern might help with COVID-19 symptoms, but it needs more testing.
research Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19
Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research 24 ARQ-234: a high affinity CD200-Fc fusion protein for the treatment of atopic dermatitis
ARQ-234, a protein designed to treat atopic dermatitis, shows increased effectiveness in early testing.
research 581 Spontaneous, Intrinsic Aging in Organ-Cultured Human Skin as Novel Ex Vivo Assay to Test Candidate Anti-Aging Actives
The document concludes that a new method has been developed to test anti-aging substances on human skin, showing that these substances can reduce skin aging signs.
research Alopecia Areata: Updates from the Mouse Perspective
Mouse models help understand alopecia areata and find treatments.
research Combination Therapies and the Theoretical Limits of Evidence-Based Medicine
The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.
research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)
Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.
research The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model
Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.
research Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata
Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
research Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro
A 3D skin model helps study wound healing better than traditional methods.
research Development and Validation of A C57BL/6 Mouse Model of Androgenetic Alopecia Through Testosterone Propionate Induction
A mouse model was created to study hair loss similar to humans.
research Experimental Assessment of 3-meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors in silico and in vivo Models
The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
research New agents for cancer chemoprevention
Over 30 potential cancer prevention treatments are being tested, with some showing promise in early research.