184 citations
,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
88 citations
,
January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
87 citations
,
March 2020 in “Australian Dental Journal” Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
49 citations
,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
36 citations
,
July 2019 in “Journal of Materials Science Materials in Medicine” Human hair keratin helps repair nerve damage in rats.
32 citations
,
January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
20 citations
,
February 2017 in “International Journal of Dermatology” Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
18 citations
,
January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
17 citations
,
March 2021 in “Expert Opinion on Biological Therapy” Use PRP and ASC-BT for hair loss and wound healing, but more research needed.
14 citations
,
July 2021 in “Biomedicines” Platelet-rich treatments can help improve wound healing and tissue repair.
10 citations
,
May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
1 citations
,
December 2019 in “Archives of the Balkan Medical Union” Injecting platelet-rich plasma into the muscle layer improves intestinal healing and reduces adhesions.
June 2026 in “Journal of Biological Engineering” Stem cell therapies are advancing quickly with new technologies and need supportive regulations for clinical use.
March 2026 in “Research Square” Polymer dot nanozymes and exosomes, with laser stimulation, speed up wound healing.
March 2026 in “Frontiers in Pharmacology” New treatments for hair loss show promise but need more testing for effectiveness and safety.
March 2026 in “Trends in Sciences” PRF and CGF are becoming more popular than PRP in regenerative medicine due to their simplicity and lack of additives.
January 2026 in “Frontiers in Cell and Developmental Biology” Platelet-derived products can help regenerate the temporomandibular joint by enhancing natural healing processes.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” Exosome therapy shows promise for hair growth with minimal side effects, but more research is needed.
May 2022 in “Acta scientific dental sciences” Platelet concentrates are useful for tissue repair in medicine and dentistry, with L-PRF showing promising results in various treatments.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
3 citations
,
January 2016 in “Annals of Dermatology” Minoxidil was the most effective treatment for hair regrowth in rats compared to Aminexil or Kerium.
21 citations
,
January 2023 in “The International Journal of Developmental Biology” The Wnt signaling pathway is crucial for regeneration and could help advance human medicine.
December 2025 in “Drug Discovery and Molecular Docking (DDMD)” Single-cell transcriptomics reveals detailed cellular diversity and key pathways in tissue regeneration.
471 citations
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October 2012 in “Cellular and Molecular Life Sciences” Understanding developmental pathways can improve wound healing treatments.
343 citations
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March 2016 in “Nature Communications” IL-17-producing γδ T cells help improve bone healing.
298 citations
,
January 2014 in “BioMed Research International” Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
91 citations
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.