S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
90 citations
,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
1 citations
,
February 2022 in “Experimental Dermatology” Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.
September 2020 in “Revista Digital de Postgrado” Platelet-rich plasma helps heal skin by using growth factors.
2 citations
,
November 2008 in “Medical Hypotheses” VEGF and its receptor might cause hair loss.
3 citations
,
July 1996 in “Archives of Dermatological Research” 1 citations
,
January 1985 in “Protides of the biological fluids” Injecting monocyto-angiotropin into hare skin increases hair growth by forming new blood vessels.
91 citations
,
July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
28 citations
,
February 1999 in “Journal of Investigative Dermatology” Urokinase, a type of protein, helps skin cells multiply faster, especially in newborn mice.
182 citations
,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
August 2020 in “CRC Press eBooks” Abnormal growth factors can cause hair and skin issues.
Some factors can either promote or inhibit hair growth.
5 citations
,
March 2017 in “Biomedical and Pharmacology Journal” Certain growth factors significantly affect hair loss in women with telogen effluvium.
5 citations
,
March 1996 in “Archives of Dermatological Research” Certain cytokines and growth factors can stop hair growth and may play a role in alopecia areata.
January 2026 in “Biochemical Pharmacology”
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
1 citations
,
October 2002 in “The Journal of Urology” 1 citations
,
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Heat shock proteins help basal cell carcinoma grow by responding to inflammation signals.
April 2017 in “Journal of Investigative Dermatology” Dermal lymphatic vessels help hair growth by affecting hair cycle phases.
September 2008 in “Kitasato medical journal” 120 citations
,
May 2012 in “Experimental Cell Research” VEGF promotes hair follicle cell growth through the VEGFR-2/ERK pathway.
1 citations
,
October 2023 in “European journal of histochemistry” Ozone and procaine boost the release of healing factors in platelet-rich plasma.
36 citations
,
July 2004 in “Apmis” Fluorescent proteins in mouse models effectively visualize tumor blood vessel growth.
January 2025 in “International Journal of Genomics” Three genes, BMP4, POSTN, and WNT5A, may help treat keloids.
23 citations
,
July 1996 in “Archives of Dermatological Research” bFGF, VEGF, and minoxidil decrease collagen production in hair cells, possibly affecting hair growth.
16 citations
,
November 2017 in “Acta dermato-venereologica” Prostanoids, like prostaglandins and thromboxane A2, can both enhance and inhibit hair growth, and understanding their effects could help treat hair disorders.
91 citations
,
March 1996 in “Archives of Dermatological Research” Certain cytokines and growth factors can inhibit hair growth and may affect alopecia areata.
2 citations
,
January 2023 in “Scientific Reports” HIF-1α is important for hair growth and could be a treatment target for hair loss.
1 citations
,
July 2024 in “Journal of Investigative Dermatology” Immune cells boost stem cell activity in hairy moles, causing more hair growth.
21 citations
,
July 2004 in “Apmis” Fluorescent proteins help visualize and understand tumor blood vessel growth.