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research Reporting on Adverse Clinical Events
Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
research Addition of Platelet-Rich Plasma to Endorectal Advancement Flap Repair Does Not Enhance the Healing of Cryptoglandular Transsphincteric Fistulas
Adding platelet-rich plasma does not improve healing of certain fistulas.
research COMPARITIVE STUDY OF TOPICAL MINOXIDIL (5%) PLUS FINASTERIDE (0.1%) VERSUS PLATELET-RICH PLASMA PLUS TOPICAL MINOXIDIL (5%) PLUS FINASTERIDE (0.1%) IN PATIENTS WITH ANDROGENIC ALOPECIA
Adding PRP to minoxidil and finasteride is more effective for hair loss.
research An effective range of polydeoxyribonucleotides is critical for wound healing quality
Classic PDRN improves wound healing quality by enhancing cell migration.
research Effects of platelet-rich plasma on in vitro hair follicle germ preparation for hair regenerative medicine
Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.
research Autologous Platelet-Rich Plasma (PRP) for Treating Androgenetic Alopecia: A Novel Treatment Protocol Standardized on 2 Cases
The new PRP treatment significantly improves hair growth.
research Trimodal Mini‐Invasive Therapy for Stable‐Phase Peyronie's Disease: A Two‐Center Real‐Life Prospective Pilot Study
PRP injections are safe but don't significantly improve Peyronie's Disease.
research 5α‐reductase inhibitors: Evaluation of their potential confounding effect on GC‐C‐IRMS doping analysis
5α-reductase inhibitors can interfere with doping tests by masking banned substances.
research PRP for androgenetic alopecia
research Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation
Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.
research 5 Alpha Reductase Inhibitors
Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.
research How Rich is Platelet Rich Plasma? A Simple Preparation Method of PRP and Its Quality According to Various Classification Systems
A simple, cost-effective method to prepare high-quality PRP is suitable for smaller medical institutions.
research Prostaglandin E2 prevents radiotherapy-induced alopecia by attenuating transit amplifying cell apoptosis through promoting G1 arrest
Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair cells.
research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research Platelet-rich plasma as a therapy for androgenic alopecia: a systematic review and meta-analysis
PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.
research MP45-12 CHRONIC ADMINISTRATION OF A LIMK2 INHIBITOR IMPROVES CAVERNOSAL VENO-OCCLUSIVE DYSFUNCTION THROUGH SUPPRESSION OF CAVERNOSAL FIBROSIS IN A RAT MODEL OF ERECTILE DYSFUNCTION AFTER CAVERNOSAL NERVE INJURY
Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
research A Monte Carlo Simulation Framework to Quantify Platelet Dose Variability in Platelet-Rich Plasma Therapies
This study presents a probabilistic framework using Monte Carlo simulations to quantify variability in platelet dose delivered (PDD) in platelet-rich plasma (PRP) therapies. By modeling PDD as a random variable influenced by platelet count, concentration factor, injected volume, and processing efficiency, the study conducted 100,000 iterations to explore uncertainty propagation. The simulations showed a right-skewed distribution of PDD with a median of 3.1 × 10^9 platelets and a coefficient of variation over 50%. Sensitivity analysis identified injected volume and concentration factor as major contributors to variability, with significant interaction effects. The findings highlight the utility of probabilistic modeling in understanding variability sources in PRP preparation and offer a framework for uncertainty quantification in similar biomedical systems.
research Effects of platelet-rich plasma in the complex therapy of patients with androgenic alopecia
Combining PRP with minoxidil significantly improves hair growth and reduces hair loss in men with androgenic alopecia.
research Discovery of Orally Available Prodrugs of Itaconate and Derivatives
New itaconate prodrugs improve its absorption and effectiveness for treating inflammation.
research Platelet Rich Plasma in Androgenic Alopecia: Where do we Stand?
Platelet Rich Plasma (PRP) shows promise for hair growth, ulcer healing, and skin rejuvenation, but more research is needed for consistent results and it's not suitable for people with certain blood conditions.
research Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.
A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.
research De novo designed bifunctional proteins for targeted protein degradation
Newly designed proteins can effectively degrade specific proteins in cells, offering a promising alternative for targeted protein degradation.
research EXOSSOMOS E PLASMA RICO EM PLAQUETAS COMO NOVAS TERAPIAS REGENERATIVAS NA ALOPECIA: UMA REVISÃO SISTEMÁTICA DE LITERATURA
Exosome and PRP therapies show promise for treating hair loss but need more research for standardization and safety.
research Effects and mechanism of platelet-rich plasma on military drill injury: a review
Platelet-rich plasma (PRP) can effectively treat military drill injuries by reducing pain and improving function.
research The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study
Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.
research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research Treatment response to conventional and novel therapies in chronic prostatitis
Combining different treatments may be needed to effectively manage chronic prostatitis.
research Process Optimization and Efficacy Assessment of Standardized PRP for Tendinopathies in Sports Medicine: Retrospective Study of Clinical Files and GMP Manufacturing Records in a Swiss University Hospital
Standardized PRP is effective for tendinopathies, with most patients improving after one injection.
research Platelet-Rich Plasma Applications in Plastic Surgery
Platelet-rich plasma is now used in plastic surgery.