August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
1 citations
,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
9 citations
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January 1990 in “Skin Pharmacology and Physiology” The method and source of keratinocytes affect the structure of reconstructed skin.
January 2011 in “Anhui nongye kexue” The vector successfully directed specific gene expression in hair follicles.
43 citations
,
September 2009 in “Stem Cells” A nonviral method was developed to label and culture human hair follicle stem cells.
4 citations
,
December 2017 in “International Journal of Biomedicine” Fibroblast transplantation improves wound healing, with dermal equivalents slightly enhancing skin regeneration.
April 2018 in “Journal of Investigative Dermatology” Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
128 citations
,
August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
1235 citations
,
December 2013 in “Nature” Two fibroblast types shape skin structure and repair differently.
32 citations
,
May 2017 in “Lasers in medical science” Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.
21 citations
,
December 2023 in “Bioengineering & Translational Medicine” Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.
3 citations
,
January 2014 Collagen XVIII and Bmx tyrosine kinase are important for hair growth and skin cancer development.
66 citations
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December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
18 citations
,
January 1994 in “Skin Pharmacology and Physiology” Human dermal fibroblasts and hair papilla cells help outer root sheath cells grow and develop properly.
March 2024 in “Advanced science” A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
The skin can still regenerate and function well even with fewer fibroblasts.
6 citations
,
October 2024 in “International Journal of Dermatology” Proinflammatory fibroblasts and vascular endothelial cells are key in keloid development.
2 citations
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May 2011 in “Pigment Cell & Melanoma Research” Collagen XVII is crucial for preventing hair and pigmentation loss by maintaining melanocyte stem cells.
3 citations
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May 1991 in “Journal of Investigative Dermatology”
15 citations
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August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
9 citations
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August 2024 in “Tissue Engineering and Regenerative Medicine” Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
29 citations
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May 1988 in “Clinical Endocrinology” Fibroblasts help understand androgen resistance at the cellular level.
September 2021 in “Morphologia” Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
6 citations
,
April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
November 2022 in “Journal of Investigative Dermatology” Fish-derived collagen may help hair grow longer and affect hair stem cells, while bovine collagen could benefit hair stem cell maintenance, potentially aiding in hair loss conditions.
January 2007 in “Linchuang pifuke zazhi” HIF-1α in fibroblasts boosts hair growth and health.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
115 citations
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February 2016 in “Nature Communications” Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
5 citations
,
September 2023 in “Journal of Cosmetic Dermatology” c-Maf positive macrophages help form hypertrophic scars by affecting fibroblasts and collagen production.
146 citations
,
July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.