218 citations
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September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
165 citations
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January 2006 in “Molecular Medicine” Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.
120 citations
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April 2019 in “The Journal of clinical investigation/The journal of clinical investigation” Both estrogens and androgens are important for health in both males and females.
48 citations
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December 2019 in “Reproductive Biology and Endocrinology” More research is needed to confirm sperm DNA fragmentation as a reliable tool for diagnosing male infertility.
38 citations
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November 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
3 citations
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November 2024 in “Egyptian Journal of Medical Human Genetics” SGK1 is important in cancer growth and treatment resistance, and targeting it could improve therapies.
3 citations
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April 2022 in “Microorganisms” People with severe hair loss (Alopecia Areata) have different scalp bacteria than healthy people, which might help predict the condition's progress.
1 citations
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February 2025 in “Journal of the Neurological Sciences” Beta-trace protein may help diagnose and predict treatment response in certain nerve disorders.
May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” Higher oxidative stress markers are linked to hair loss in post-COVID-19 patients.
37 citations
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August 2024 in “Current Issues in Molecular Biology” Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
37 citations
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November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
32 citations
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August 2020 in “American Journal Of Pathology” S100A4 promotes aggressive ovarian cancer and is a potential treatment target.
21 citations
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March 2023 in “Journal of Crohn s and Colitis” Microvascular damage and platelet issues persist in ulcerative colitis remission, helping assess disease states.
13 citations
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October 2019 in “Journal of lasers in medical sciences” CO2 laser treatment for aging skin significantly changes immune system-related genes.
13 citations
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August 2000 in “Blood” Measuring minimal residual disease on day 15 helps identify high-risk leukemia patients.
12 citations
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September 2022 in “Foods” Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.
11 citations
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September 2024 in “Journal of Advanced Research” 3D-bioprinting models of pancreatic cancer could help personalize treatments but need more testing.
11 citations
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January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
9 citations
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April 2022 in “Cell Communication and Signaling” High S100A4 levels worsen glioblastoma by promoting blood vessel growth.
6 citations
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April 2024 in “Health Science Reports” Younger patients with severe alopecia areata often have nail problems.
6 citations
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November 2020 in “Clinical Cosmetic and Investigational Dermatology” Both concentrations of triamcinolone acetonide are effective for hair regrowth in patchy alopecia areata, but 5 mg/mL is recommended to reduce side effects.
3 citations
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June 2023 in “Frontiers in Medicine” A new model uses specific blood markers to predict if children's hair loss will return.
2 citations
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September 2024 in “Diagnostics” A new method accurately measures cell changes in breast cancer.
2 citations
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May 2023 in “Cancer medicine” KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
1 citations
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April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
October 2023 in “Cancers” Skin cancer in sun-exposed areas is more likely to come back.
August 2023 in “Tzu Chi Medical Journal” Iron deficiency is the main cause of hair loss in women, and iron supplements started within 6 months can improve hair health.
August 2022 in “IntechOpen eBooks” Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
March 2025 in “Archives of Dermatological Research” miR-155-5p can help diagnose and track alopecia areata severity.
91 citations
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May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.