June 2023 in “Lithuanian University of Health Sciences” Acne tarda is more common in women and those with darker skin, often linked to hormonal imbalances, and requires tailored treatment based on severity.
January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” Metformin may improve acanthosis nigricans by reducing insulin resistance.
17 citations
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June 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
December 2020 in “Benha Journal of Applied Sciences” People with severe acne tend to have higher levels of betatrophin.
22 citations
,
October 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Combining isotretinoin and dapsone effectively treated a challenging scalp condition.
April 2026 in “International Journal of Homoeopathic Sciences” Individualized homeopathic treatment improved acne when conventional methods failed.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Androgens increase growth factors in skin cells, which may lead to acne.
46 citations
,
November 2004 in “Lipids” PPARs help regulate skin health and could be used to treat skin disorders.
200 citations
,
August 2009 in “Experimental dermatology” Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
1 citations
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September 2001 in “PubMed” Acitretin treats severe skin conditions but requires careful monitoring due to serious side effects.
March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” Topical retinoids are important for treating acne effectively and safely.
14 citations
,
January 2020 in “Dermatology Online Journal” Some dietary supplements, like vitamins B6/B12, iodine, whey protein, and muscle-building products, can cause or worsen acne.
2 citations
,
August 2021 in “Australasian Journal of Dermatology” Acne in adult women is often linked to polycystic ovary syndrome, especially in those who are younger, have premenstrual acne flare-ups, and irregular periods.
8 citations
,
August 2015 in “Experimental Dermatology” Hidradenitis suppurativa may involve gut and oral bacteria, suggesting targeted treatments could help.
1 citations
,
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.
August 2023 in “Dermatology Reports” Acne not improved by usual treatments may indicate a genetic disorder.
January 2024 in “MEDS Chinese Medicine” Acupuncture can effectively treat acne.
April 2021 in “Journal of Investigative Dermatology” People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.
78 citations
,
June 1989 in “The Journal of dermatologic surgery and oncology” Acne keloidalis is a chronic skin condition on the back of the neck in young black men, needing surgery for severe cases.
November 2025 in “Cureus” PCOS-related acne can be managed by targeting hormones and insulin resistance.
September 2019 in “Journal of Investigative Dermatology” PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.
233 citations
,
November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
2 citations
,
January 2014 in “Advanced Biomedical Research” Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.
March 2023 in “Journal of the American Academy of Dermatology” Treating underlying conditions and using antifungals effectively resolve Pityrosporum folliculitis in immunocompromised people.
1 citations
,
June 2011 in “Journal of Dermatological Case Reports” Shaving and applying erythromycin cream and clotrimazole powder effectively treated trichomycosis axillaris.
7 citations
,
September 1988 in “Baillière's clinical obstetrics and gynaecology” Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
14 citations
,
January 2015 in “Acta dermato-venereologica” Acitretin significantly reduced inflammatory attacks in a woman with Naevus Comedonicus Syndrome but caused side effects.
April 2026 in “Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi” Severe acne patients have higher inflammatory markers than healthy people.
July 2005 in “SKINmed/Skinmed” BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.