32 citations
,
September 2018 in “Clinical Obstetrics and Gynecology” Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
195 citations
,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
155 citations
,
December 2003 in “British Journal of Dermatology” Hair loss increases with age; alcohol raises risk, more female partners lowers it.
65 citations
,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
30 citations
,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
29 citations
,
February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications” New method detects finasteride in plasma quickly and accurately without clean-up.
24 citations
,
October 2008 in “International Braz J Urol” Lovastatin doesn't improve lower urinary tract symptoms treatment.
23 citations
,
June 2017 in “Drug Design Development and Therapy” Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
23 citations
,
January 2007 in “Archives of Andrology” Finasteride may negatively affect male fertility.
23 citations
,
December 1995 in “Archives of Dermatology” Combination therapy improves hair growth in advanced hair loss.
22 citations
,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
19 citations
,
May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” Reliable method detects finasteride in human plasma at low doses.
13 citations
,
November 2014 in “Toxicology Letters” Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
10 citations
,
December 2008 in “Journal of Clinical Neuromuscular Disease” Finasteride can cause muscle pain and high creatine kinase levels, but stopping the medication may resolve symptoms.
9 citations
,
August 2019 in “Clinical genitourinary cancer” Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.
9 citations
,
January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
8 citations
,
July 2018 in “Analytical sciences” Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
7 citations
,
March 2015 in “The American Journal of the Medical Sciences” Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
3 citations
,
October 2018 in “Experimental and Therapeutic Medicine” Stopping tamsulosin one month before cataract surgery reduces eye surgery complications in rats.
2 citations
,
March 2018 in “Current Opinion in Urology” 5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
August 2009 in “Australian Prescriber” Eculizumab helps reduce blood transfusions and stabilize hemoglobin but increases infection risk and is expensive.
January 2016 in “Elsevier eBooks” Finasteride helps hair growth.
44 citations
,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
23 citations
,
January 2017 in “Current Rheumatology Reports” Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.
2 citations
,
June 2000 in “Journal of Oral and Maxillofacial Surgery” Hair transplantation techniques have improved over time, leading to natural-looking results and high graft survival rates, making it a popular treatment for hair loss.
1 citations
,
March 2004 in “Military Medicine” The retired colonel's ankle swelling was caused by a reaction to the antibiotic levofloxacin.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
5 citations
,
June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.