research Single-cell chromatin landscapes of mouse skin development
The study maps how genes are regulated during mouse hair growth.
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research Hematopoietic Stem Cells: Nature and Niche Nurture
Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease
Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
research Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems
Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.
research AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response
AI improves biomaterial design by making it faster, cheaper, and more effective for personalized medicine.
research Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications
Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
research Androgens modulate endometrial function
Androgens affect the function and health of the endometrium.
research A New Heterozygous Variant of c.1225_1227delTTC (p.Phe409del) in Insulin Receptor Gene Associated with Severe Insulin Resistance and Hyperandrogenemia in an Adolescent Female with Type A Severe Insulin Resistance Syndrome
A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.
research TOWARDS NOVEL DIAGNOSTIC MARKER BASED ON BREAST ARTERIAL CALCIFICATIONS
Detecting early breast arterial calcifications can help assess cardiovascular disease risk.
research Biological and mechanical influence of three-dimensional microenvironment formed in microwell on multicellular spheroids composed of heterogeneous hair follicle stem cells
3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.
research Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing
Low-coverage sequencing is a cost-effective way to identify genes related to wool traits in rabbits.
research Microneedles-A new paradigm in transdermal delivery of therapeutic agents
Microneedles offer a painless, effective way to deliver drugs through the skin.
research 609 Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration
Activating TRPA1 reduces scarring and promotes tissue regeneration.
research Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells
Different types of skin stem cells can change and adapt, which is important for developing new treatments.
research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)
The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
research Shushing down the epigenetic landscape towards stem cell differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
research Vitamin D, Lipid Metabolism and Prostate Cancer
Vitamin D may help regulate cholesterol and influence prostate cancer development.
research Diagnosis and treatment of polycystic ovarian syndrome: an update
PCOS is managed with medication, lifestyle changes, and a healthy diet.
research Clinical efficacy and safety of Kanglaite injection, adjuvant cemcitabine and cisplatin chemotherapy for advanced non-small-cell lung cancer: A systematic review and meta-analysis
Kanglaite injection with chemotherapy improves treatment and reduces side effects for advanced lung cancer.
research A preliminary study of markers for human hair follicle melanin stem cell
Researchers identified potential markers for human hair color stem cells.
research Embryology, Histology, and Physiology of the Hair Follicle
The document explains how hair follicles develop, their structure, and how they grow.
research Trichodystrophies: A hair-raising differential diagnosis
The guide helps doctors diagnose hair problems by suggesting a thorough patient history, physical exams, and various diagnostic tools.
research Chemotherapy and Cutaneous Drug Reactions
Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
research Olfactory epithelium regeneration and homeostasis: cellular and molecular mechanisms and novel methodological advances
The olfactory epithelium can regenerate throughout life, aided by specific cells, genes, and new research methods.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research Progress and perspectives on hydrogel-assisted skin organoids
Hydrogel-based methods improve skin organoid development for medical and research applications.
research A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin
Mouse and human skin development share similar fibroblast timelines.
research Nanotechnological reprogramming of the pathological skin microenvironment in scar formation and atopic dermatitis
Nanotechnology could improve treatment for scars and atopic dermatitis by targeting skin issues more effectively.
research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation
SPT6 prevents excessive skin inflammation by blocking a feedback loop.