research Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development
A new method, iSiMPRe, effectively identifies key protein regions in cancer genes, highlighting potential drug targets.
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360-390 / 1000+ resultsresearch Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis
The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.
research Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review
research Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Skin acetyl-CoA synthesis is crucial for overall lipid balance.
research Harnessing Microbiome, Bacterial Extracellular Vesicle, and Artificial Intelligence for Polycystic Ovary Syndrome Diagnosis and Management
Microbiome analysis, BEVs, and AI can improve PCOS diagnosis and treatment.
research Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development
Spermidine is essential for plant growth and adaptation to stress.
research A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia
The study identified 12 potential biomarkers for hair loss and how they affect hair growth.
research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions
Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
research Hormonal interventions in skin wounds – a mini review
Hormones can improve wound healing by regulating the healing process.
research Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety
CBD may improve skin and hair health, but its effective use and safety need more research.
research Dual deficiency of melatonin and dihydrotestosterone promotes stromal cell damage and mediates prostatitis via the cGAS-STING pathway in sleep-deprived mice
Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.
research https://researchopenworld.com/genetics-of-hidradenitis-suppurativa/#
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
research Direct Reprograming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Pseudomonas aeruginosa heme metabolites biliverdin IXβ and IXδ are integral to lifestyle adaptations associated with chronic infection
Biliverdin IXβ and IXδ help Pseudomonas aeruginosa adapt to chronic infections.
research Proteomics as a tool to improve novel insights into skin diseases: what we know and where we should be going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
research A skin organoid-based infection platform identifies an inhibitor specific for HFMD
NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
research Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020
PRP shows promise in treating joint and spine issues, but translating lab results to humans is challenging.
research Macrophage Related Chronic Inflammation in Non-Healing Wounds
Macrophage issues cause chronic wound inflammation, but therapies can help.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research Distinguishing Mouse Strains by Proteomic Analysis of Pelage Hair
Proteomic analysis can identify genetic differences in mouse hair, helping understand hair defects and variations.
research Bacteria Display Differential Growth and Adhesion Characteristics on Human Hair Shafts
Human hair shafts inhibit Gram-positive bacteria growth but not Gram-negative bacteria.
research Fetuin-A: A Major Fetal Serum Protein that Promotes “Wound Closure” and Scarless Healing
Fetuin-A helps wounds heal without scars by promoting cell movement.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery
Coumarin derivatives cause skin irritation, but coumarin itself does not.
research Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review
Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
research The therapeutic, diagnostic, and prognostic values of extracellular vesicles (exosomes) in dermatology: A systematic review
Extracellular vesicles show potential in dermatology, but more research is needed for validation.
research Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases
Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.
research PolyQ length co-evolution in neural proteins
PolyQ repeats in neural proteins evolve together, affecting brain function and disease.