277 citations
,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
77 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
29 citations
,
January 2020 in “BioMed Research International” Sinapic acid may help fight obesity and promote hair growth.
March 2026 in “The Journal of Steroid Biochemistry and Molecular Biology” Deleting vitamin D and calcium receptors in skin cells increases skin cancer risk by reducing DNA repair and stress response.
16 citations
,
March 1986 in “Biochemical Pharmacology”
5 citations
,
January 2020 in “The mental health clinician” Vitamin D supplements may reduce hair-pulling in people with Trichotillomania.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Men with early baldness often have low vitamin D levels.
74 citations
,
July 1979 in “Lancet” Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
42 citations
,
July 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
August 2025 in “Scientific Reports” C4BPA protein may link acne severity and insulin resistance.
18 citations
,
October 2009 in “Endocrinology” Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.
1 citations
,
December 2022 in “Archives of Dermatological Research” Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
19 citations
,
March 2021 in “Experimental and Therapeutic Medicine” Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
87 citations
,
January 1996 in “Journal of cellular biochemistry” Over 30 potential cancer prevention treatments are being tested, with some showing promise in early research.
10 citations
,
February 2014 in “Fitoterapia” Pomiferin may improve skin and hair by increasing important protein production.
December 2020 in “Benha Journal of Applied Sciences” People with severe acne tend to have higher levels of betatrophin.
6 citations
,
March 2023 in “Journal of Cosmetic Dermatology” Low levels of BDNF and vitamin D are linked to higher depression in alopecia areata and vitiligo patients.
7 citations
,
March 2002 in “AIDS” Indinavir, especially with vitamin A, may cause bone changes, but switching to nelfinavir can reduce these effects.
January 2023 in “Side effects of drugs annual” Some vitamins, amino acids, and alternative medicines can cause serious side effects, including bone, muscle, and skin issues, and healthcare professionals should be aware of these risks.
7 citations
,
January 2022 in “Scientific Reports” Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.
1 citations
,
May 2019 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.
1 citations
,
February 2026 in “Clinics in Dermatology” Vitamins help hair mainly if you have a deficiency; too much can cause hair loss.
37 citations
,
August 2011 in “Journal of Bone and Mineral Research” A girl had rickets due to a gene mutation affecting vitamin D response.
1 citations
,
January 2007 in “Side effects of drugs annual” Dermatological treatments can have significant side effects, including allergic reactions, sexual dysfunction, and increased cancer risk.
18 citations
,
October 1986 in “PubMed” Alpha-tocopherol does not prevent hair loss from doxorubicin.
July 2021 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” Low vitamin D levels are linked to more skin problems.
48 citations
,
June 2013 in “Journal of Dermatological Science” Valproic acid may help hair grow and could be a safe treatment for hair loss.
January 2025 in “Indian Journal of Paediatric Dermatology” Vitamin D deficiency is common in children with and without alopecia areata, and more research is needed.
31 citations
,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.