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research Decision letter: Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

October 2016

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

research Matrix-Degrading Type II Transmembrane Serine Protease Matriptase: Its Role in Cancer Development and Malignancy

12 citations , October 2006

Matriptase imbalance contributes to cancer development and spread.

research GENOTYPE ? PHENOTYPE CORRELATIONS IN CUTANEOUS MELANOMA PATIENTS CARRIER OF THE MITF p.E318K PATHOGENIC VARIANT

May 2019 in “CINECA IRIS Institutial Research Information System (University of Genoa)”

MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.

research Matriptase-2, A Novel Suppressor of Hepcidin.

November 2009 in “Blood”

Matriptase-2 helps control iron levels by suppressing hepcidin, and its deficiency can cause iron-deficiency anemia.

research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted ^99mTc-Radioimaging Agents

148 citations , April 2009 in “Molecular Pharmaceutics”

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

research Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer

22 citations , August 2020 in “Cells”

TGM3 is important for skin and hair structure and may help diagnose cancer.

research Triton modified polyethyleneimine conjugates assembled with growth arrest-specific protein 6 for androgenetic alopecia transdermal gene therapy

February 2023 in “Materials today bio”

The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.

research Neoadjuvant Therapy with Disitamab Vedotin in Treating Muscle-Invasive Bladder Cancer: A Case Report

January 2022 in “SSRN Electronic Journal”

Gemcitabine and Disitamab Vedotin effectively and safely reduced bladder cancer in a patient.

research Identification of a Novel MPL Loss of Function Mutation in a Patient with Cyclic Thrombocytopenia and Characterization of This Syndrome

4 citations , December 2016 in “Blood”

A new gene mutation may cause cyclic thrombocytopenia by affecting platelet production.

research TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

February 2026 in “Advanced Science”

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

research Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.

26 citations , June 2003 in “PubMed”

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

research Abstract P5-11-11: A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia (CIA)

February 2017 in “Cancer Research”

Topical calcitriol appears safe and may reduce hair loss during chemotherapy.

research Recurrent MBTPS2 variant c.970+5G>A in IFAP syndrome: a mutational hotspot

April 2026 in “Human Genome Variation”

The MBTPS2 gene variant c.970+5G>A is a common mutation causing IFAP syndrome.

research Studies on basal cell carcinoma with emphasis on the role of the human homologue of the Drosophila patched gene

November 1997 in “Open Archive (Karolinska Institutet)”

PTCH gene mutations contribute to basal cell carcinoma development.

research Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2

55 citations , June 2014 in “Nature Communications”

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers

75 citations , June 2007 in “Journal of Biological Chemistry”

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation

23 citations , December 2013 in “Molecular cancer therapeutics”

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype

10 citations , September 1997 in “Molecular carcinogenesis”

Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles*

34 citations , May 2001 in “Endocrinology”

Mrp3 helps in wound healing and hair growth.

research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer

February 2026 in “Oncology Reviews”

Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.

research Three Cases of Hemodialysis Patients with Advanced Gastric Cancer Treated with Paclitaxel and Nab Paclitaxel

1 citations , October 2014 in “Annals of oncology”

Paclitaxel and nab-paclitaxel can be safe and effective for advanced gastric cancer patients on hemodialysis.

research Delayed hair cycle in mnd2 mutant mice lacking HtrA2 serine protease activity

December 2022 in “Biochemical and Biophysical Research Communications”

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

research Análise dos níveis de metilação e de polimorfismos genéticos dos genes GSTP1, MGMT, VDR e AR em pacientes com câncer de próstata

May 2024 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)”

Certain gene combinations may affect prostate cancer risk, and GSTP1 methylation is linked to tumor aggressiveness.

research P7 p63, K14 and p53 expression in epithelial layers of tumor-distant oral mucosa in patients with oral squamous cell carcinoma

March 2010 in “European Journal of Cancer Supplements”

research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

5 citations , August 2019 in “iScience”

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable Stage III Non-Small Cell Lung Cancer

research A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable Stage III Non-Small Cell Lung Cancer

January 2025 in “Recent Patents on Anti-Cancer Drug Discovery”

The treatment showed high response rates and was well-tolerated, potentially extending patient survival.

research Betapapillomaviruses in the anal canal of HIV positive and HIV negative men who have sex with men

2 citations , May 2014 in “BMC Infectious Diseases”

HIV-positive men who have sex with men have a higher rate of anal beta-papillomavirus infections.

P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss

research P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss

5 citations , January 2022 in “PloS one”

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

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