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A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

Human skin can make serotonin and melatonin.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

A new method efficiently modifies alkenes to create useful medicinal compounds.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

BrdU speeds up hair follicle aging and reduces hair quality.

Cepharanthine can potentially treat gastric cancer by stopping tumor growth.

OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

A method was created to measure oxymatrine in human blood.

Understanding metabolic changes in dormant cells can help treat cancer.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Polyamines are important in deciding hair follicle stem cell behavior, affecting hair growth and loss.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

Hepatitis C and alcohol abuse may lead to porphyria cutanea tarda.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

The method produces finasteride with a 92% yield.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.

Effective treatment for UFT overdose includes antibiotics and G-CSF, with bone marrow biopsy and transfusion as backup options.

5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Hair growth genes work better with more glucose due to changes in gene-regulating markers.