research Cyproterone Acetate in the Treatment of Sexual Disorders: Pharmacological Base and Clinical Experience
Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
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research Transcranial focused ultrasound-mediated unbinding of phenytoin from plasma proteins for suppression of chronic temporal lobe epilepsy in a rodent model
Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
research Screen steroid 5 alpha-reductase inhibitors in vitro by high performance liquid chromatography
The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
research P62 Drug induced hypothyroidism in patients receiving treatment for multi-drug resistant tuberculosis
People from iodine-deficient areas are more likely to develop hypothyroidism when treated for multi-drug resistant tuberculosis.
research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Interventions for Hirsutism
Oral contraceptives help mild hirsutism, while flutamide and spironolactone help severe cases.
research (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production
The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
research 43647 Treatment of Refractory Folliculitis Decalvans with the Topical JAK Inhibitor Tofacitinib
Topical tofacitinib helped a man with severe scalp condition after other treatments failed.
research Improved synthesis of finasteride
The new method makes finasteride production cheaper and safer for industry.
research The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting
Finasteride may help reduce impulsivity caused by pramipexole.
research Focus sulla finasteride: efficacia, meccanismi e raccomandazioni per l'uso clinico
Finasteride effectively treats benign prostatic hyperplasia by reducing prostate size and improving urinary symptoms.
research A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive.
The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
research Development of Stable and Simple Finasteride 333-μg/mL Suspensions that Minimize Occupational Exposure.
A stable and simple finasteride suspension was developed that retains over 94.3% of its concentration for up to 90 days and doesn't significantly increase occupational exposure, but safety measures are still advised.
research Forsythiaside A Activates AMP-Activated Protein Kinase and Regulates Oxidative Stress via Nrf2 Signaling
Forsythiaside A helps protect cells and liver from damage by reducing oxidative stress and boosting antioxidants.
research Effectiveness and safety of finasteride in male chronic pelvic pain syndrome
Finasteride effectively reduces symptoms of male chronic pelvic pain syndrome with few side effects.
research The urologic impact of long-term finasteride 1-mg use for androgenic alopecia: a matched-cohort database analysis
This study analyzed the urologic impact of long-term finasteride 1 mg (F1) use in 3,470 men with androgenic alopecia (AA) compared to a matched cohort of 3,470 men with AA not using F1. The results showed that while there was no significant difference in erectile dysfunction (ED) diagnosis between the groups, those on F1 were more likely to be prescribed phosphodiesterase type 5 inhibitors (PDE5i) and received them approximately 230 days earlier than non-F1 users. F1 use did not significantly affect benign prostatic hyperplasia (BPH) diagnosis or treatment rates but was associated with decreased prostate cancer (PC) and elevated prostate-specific antigen (PSA) diagnosis rates. The study suggests the need for further research on the urologic effects of chronic F1 use in AA patients.
research Further errors in polymorph identification: furosemide and finasteride
Errors found in identifying furosemide and finasteride polymorphs due to incomplete data.
research [The treatment of epilepsies with Convulsofin].
Convulsofin effectively treats primary epilepsy but has some side effects.
research P163 : Clinical efficacy of 2.5mg/day finasteride in female pattern hair loss
2.5 mg/day finasteride effectively treats female pattern hair loss.
research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research A study on the extracts of Cuscuta reflexa Roxb. in treatment of cyclophosphamide induced alopecia
Cuscuta reflexa extracts helped regrow hair in rats with drug-induced hair loss.
research Sensitive bromatometric assay methods for finasteride in pharmaceuticals
Three cost-effective methods accurately measure finasteride in pharmaceuticals, better than current techniques.
research Efficacy and Safety of Treatment with Combine Mycophenolate Mofetil and Corticosteroid for Lupus Nephritis:A Multicenter Open-label Study
The treatment with Shunyou and prednisone is effective and safe for lupus nephritis.
![Influence of FHIT on Benzo[a]pyrene-Induced Tumors and Alopecia in Mice: Chemoprevention by Budesonide and N-Acetylcysteine](/images/research/f8f56777-f891-4879-8c45-c87d6aa82563/small/35499.jpg)
research Influence of FHIT on benzo[ a ]pyrene-induced tumors and alopecia in mice: Chemoprevention by budesonide and N -acetylcysteine
Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.
research Doxazosin + finasteride in BPH with TPV ??? 25mL
research Desferrioxamine treatment of aceruloplasminemia: Long‐term follow‐up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research PO:17:252 | The choice between belimumab and anifrolumab: analysis of a monocentric cohort
The choice between belimumab and anifrolumab for treating lupus depends on the patient's specific symptoms.
research High‐dose mizoribine treatment for adolescents with systemic lupus erythematosus
High-dose mizoribine effectively controls symptoms in adolescents with lupus while reducing steroid use, with manageable side effects.
research The Influence of Finasteride on Mean and Relative Spectral Density of EEG Bands in Rat Model of Thioacetamide-Induced Hepatic Encephalopathy
Finasteride may protect brain and improve behavior in rats with liver failure.
research 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis
11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.