research Analysis of 72,469 UK Biobank exomes links rare variants to male-pattern hair loss
Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.
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research Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes
Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
research Maternal iron status in early pregnancy and DNA methylation in offspring: an epigenome-wide meta-analysis
A mother's iron levels early in pregnancy can influence the DNA makeup of her child, potentially affecting the child's health.
research Use of autologous platelet-rich plasma in androgenetic alopecia in women: a systematic review and meta-analysis
PRP injections may help increase hair density in women with hair loss, but more research is needed.
research Decision letter: Quantitative mapping of human hair greying and reversal in relation to life stress
Hair can naturally regain color, and stress might influence greying and its reversal.
research 410 Oral dysbiosis in palmoplantar pustulosis patients with arthro-osteosis
People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.
research 414 A fitst-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and fluorescence contrast in skin cancer
BLZ-100 is safe for use in skin cancer surgery and may help identify cancerous tissue.
research 1331 Glutathione (GSH) distribution by quantitative MALDI imaging in reconstructed human skin upon activation of GSH biosynthesis by Nrf2 pathway activator
Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
research Development of methods for identification and quantitative determination of active substances in the medicated cosmetic cream for use in trichology
Researchers developed a method to measure active ingredients in a hair loss treatment cream.
research 730 M2 macrophages promote wound induced hair neogenesis through the production of growth factors
M2 macrophages help hair regrowth in wounds by making growth factors.
research 695 Using MALDI-MSI analysis to study distribution of FOL-005, a potent, novel inhibitor of human hair growth, after subcutaneous injection in mice
FOL-005, a new substance, was found to reduce hair growth without toxicity when injected into skin, suggesting it could be used to treat excessive hair growth.
research Past, present, and future of global research on artificial intelligence applications in dermatology: A bibliometric analysis
AI in dermatology is growing rapidly, showing promise in diagnosing skin conditions as accurately as dermatologists.
research Self-management in the post-hair transplantation recovery period among patients with androgenetic alopecia: A qualitative study
Following hair transplant surgery, proper self-care is crucial for successful recovery and hair growth.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
research A rapid screening LC‐MS/MS method based on conventional HPLC pumps for the analysis of low molecular weight xenobiotics: application to doping control analysis
A quick method was developed to detect banned substances in urine for doping control.
research Efficacy and safety of trastuzumab deruxtecan in the treatment of HER2-low/positive advanced breast cancer: a single-arm meta-analysis
Trastuzumab deruxtecan is effective for advanced breast cancer but has side effects like nausea and fatigue.
research Two-dimensional electrophoretic analysis of human hair keratins, especially hair matrix proteins
The method effectively analyzes human hair proteins, especially nonfilamentous ones.
research STABILITY-INDICATING MICELLAR ELEKTROKINETIC CHROMATOGRAPHY METHOD FOR DETERMINATION OF FINASTERIDE IN PHARMACEUTICAL PREPARATIONS
Method accurately measures finasteride concentration in medicine.
research Analysis of Trend of Studies on Microneedle Treatment System (MTS)
Microneedle Treatment System is effective for hair growth and skin improvement with no serious side effects, but more research is needed.
research Efficacy and safety of minoxidil therapy: A systematic review and meta-analysis weighing the benefits against the risk of hypertrichosis
Minoxidil is effective for hair regrowth, and its benefits outweigh the risk of extra hair growth.
research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis
DRDE-07 shows promise for treating skin diseases due to its favorable properties.
research Comparative Efficacy of Oral and Topical 5-Alpha Reductase Inhibitors in Reducing Dihydrotestosterone levels across Men with Androgenetic Alopecia: A Network Meta-Analysis incorporating Post-Hoc Analyses of Randomized Clinical Trial Data
Oral and topical 5-alpha reductase inhibitors affect DHT levels and hair density differently in treating hair loss.
research The Efficiency of Platelet-Rich Plasma (PRP) in Treating Post-Burn and Surgical Scars: A Meta-Analysis Study
PRP may help reduce scar symptoms like pain and itching after six months.
research A Qualitative Review of Misinformation on Alopecia
Misinformation about alopecia can lead to poor treatment, so it's important for healthcare professionals to correct myths.
research 3: Multimodal Molecular Analysis Reveals Divergent Trajectories Of Wound Regeneration Versus Fibrosis
Verteporfin treatment in mice led to complete skin healing without scarring.
research Original article / Article original External post mortem artefact: a key issue in hair result interpretation
Hair test results can be misleading due to external contamination, so they shouldn't be used alone to assess long-term drug use.
research Molecular genetics of androgen insensitivity
Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
research Assessing finasteride-associated sexual dysfunction using the FAERS database
Finasteride and dutasteride increase sexual dysfunction reports.
research Interventions for central serous chorioretinopathy: a network meta-analysis
No single treatment is clearly effective for central serous chorioretinopathy.
research LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure
Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.