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Thiadiazole chitosan conjugates improve hair manageability, moisture, and protection in conditioners.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Tsc2-deficient stem cells can help understand and treat TSC-related tumors.

A new compound was effective for imaging prostate cancer in rats.

Testosterone reduces knee flexibility by affecting relaxin receptors.

A new mutation in the KRT86 gene causes a hair disorder with variable expression.

TCDD changes skin cell growth and keratin production in mice.

The method effectively detects MeT and TP in dried blood spots after cream application.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Tofacitinib is a promising treatment for children with rheumatic diseases.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.

Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.

RTA 408 cream protects mice from radiation skin damage.

A 2-year-old girl with a rare vitamin D disorder had rickets and hair loss, but treatment was ineffective due to poor compliance.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

KSR1 is crucial for certain skin tumor formation and could be a cancer therapy target.

RT1640 treatment reverses gray hair and promotes hair growth in mice.

pbn-STAC effectively finds strategies for cellular reprogramming using deep reinforcement learning.

SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.

A new DSG4 gene mutation causes hair defects in a young girl.

The TG5 gene affects beef cattle weight, and the CC genotype leads to higher weights.