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GlossaryRaman spectroscopy

technique using laser light to analyze molecular vibrations

Raman spectroscopy is a technique used to study the vibrational, rotational, and other low-frequency modes in a system. It involves shining a laser on a sample and analyzing the scattered light to gain information about the molecular composition and structure. This method is valuable in various fields, including chemistry, biology, and materials science, for identifying substances and understanding molecular interactions.

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research Conformational differences in protein disulfide linkages between normal hair and hair from subjects with trichothiodystrophy: A quantitative analysis by Raman microspectroscopy

53 citations , March 2006 in “Biopolymers”

TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

research Discrimination between basal cell carcinoma and hair follicles in skin tissue sections by Raman micro-spectroscopy

25 citations , November 2010 in “Journal of Molecular Structure”

Raman micro-spectroscopy can help distinguish basal cell carcinoma from hair follicles in skin tissue.

research Experiments in Raman Spectroscopy on Hair Follicles from Females with Androgenetic Alopecia

June 2012 in “International journal of scientific research”

Hair follicles in androgenetic alopecia show no chemical changes, only size reduction.

Measuring Changes in Chemistry, Composition, and Molecular Structure Within Hair Fibers by Infrared and Raman Spectroscopic Imaging

research Measuring changes in chemistry, composition, and molecular structure within hair fibers by infrared and Raman spectroscopic imaging

42 citations , January 2011 in “Journal of Biomedical Optics”

Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.

research Raman spectroscopy and electronic microscopy structural studies of Caucasian and Afro human hair

25 citations , May 2019 in “Heliyon”

Hair treatments cause significant structural changes, especially with excessive heat, regardless of ethnicity.

Characterization of Human Ovarian Teratoma Hair Using AFM, FT-IR, and Raman Spectroscopy

research Characterization of human ovarian teratoma hair by using AFM, FT‐IR, and Raman spectroscopy

3 citations , April 2011 in “Microscopy research and technique”

Teratoma hair is similar to scalp hair but has a rougher surface and lower adhesive force.

research Raman investigation of in vivo radiation exposure on melanin in murine hair

2 citations , March 2025 in “PNAS Nexus”

Raman spectroscopy can detect radiation exposure in mouse hair with high accuracy for up to 7 days.

research A Raman spectroscopy investigation of the resilience of hair cuticular scales under uniaxial stress

March 2026 in “Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials”

Hair cuticles remain stable and resilient under stress due to strong protein content and crosslinking.

research Analysis of cosmetic residues on a single human hair by ATR FT-IR microspectroscopy

32 citations , February 2018 in “Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy”

Cosmetic residues on individual hairs can be identified and differentiated using ATR FT-IR microspectroscopy.

research Accessing Properties of Molecular Compounds Involved in Cellular Metabolic Processes with Electron Paramagnetic Resonance, Raman Spectroscopy, and Differential Scanning Calorimetry

5 citations , September 2023 in “Molecules”

These methods help understand cell structures and reactions.

research Photoinduced formation of thiols in human hair

14 citations , September 2016 in “Journal of Photochemistry and Photobiology B Biology”

UV exposure damages hair, increasing thiols and altering protein structure.

research The Anti-Flyaway/Frizz Effect by Inducing the α-Helical Structure Transition of Hair

October 2024 in “Cosmetics”

ATG effectively reduces hair frizz without damaging hair strength.

research Structural and Molecular Hair Abnormalities in Trichothiodystrophy

71 citations , May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology”

TTD hair brittleness is caused by multiple structural abnormalities.

Plain Language Summaries of Dermatological Studies

research Plain Language Summaries

June 2014 in “British Journal of Dermatology”

Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.

research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging

132 citations , January 2017 in “International Journal of Molecular Sciences”

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

A Review of Aging and an Examination of Clinical Methods in the Assessment of Aging Skin. Part 2: Clinical Perspectives and Methods

research A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part 2: Clinical perspectives and clinical methods in the evaluation of ageing skin

78 citations , September 2008 in “International Journal of Cosmetic Science”

The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.

research Penetration and Distribution in Human Skin Focusing on the Hair Follicle

1 citations , July 2005 in “Drugs and the pharmaceutical sciences”

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

research Cornification

September 2018

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

Scientific Highlights from the Society for Investigative Dermatology 2010 Annual Meeting

research Abstracts from the ASA 40thAnnual Meeting

April 2015 in “Andrology”

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

How Different Is Human Hair? A Critical Appraisal of Global Hair Fibre Characteristics and Properties Towards Defining a More Relevant Framework for Hair Type Classification

research How different is human hair? A critical appraisal of the reported differences in global hair fibre characteristics and properties towards defining a more relevant framework for hair type classification

8 citations , November 2022 in “International Journal of Cosmetic Science”

Human hair varies widely and should be classified by curl type rather than race.

research Advances in the Chemical Structure of the Hair Surface, Surface Forces and Interactions

1 citations , March 2021

Understanding hair surface properties is key for effective hair care products.

research Flexabrasion Applied to the Evaluation of the Photodegradation of Hair Fibers

December 2021 in “Cosmetics”

research Novel Placenta-Derived Liquid Product Suitable for Cosmetic Application Produced by Fermentation and Digestion of Porcine or Equine Placenta Using Lactic Acid Bacterium Enterococcus faecalis PR31

5 citations , January 2024 in “Fermentation”

The new placenta-derived liquid improves skin moisture better than traditional extracts.

research Repeatable Perming via Thiol–Michael Click Reaction: Using Amide Derived from Maleic Acid and Cystine

January 2026 in “Molecules”

A new perming method is less damaging to hair and works as well as traditional methods.