research Rapamycin but not acarbose decreases age-related loss of outer hair cells in the mouse Cochlea
Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.
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540-570 / 1000+ resultsresearch Combined C3b and Factor B Autoantibodies and MPGN Type II
The FDA did not approve certain drugs for prostate cancer prevention due to concerns about their effectiveness and potential risks.
research Simvastatin-induced myoglobinuric acute kidney injury following ciclosporin treatment for alopecia universalis
A woman developed severe kidney injury from using simvastatin with ciclosporin, highlighting the need for careful monitoring when combining these drugs.
research Trimodal Mini‐Invasive Therapy for Stable‐Phase Peyronie's Disease: A Two‐Center Real‐Life Prospective Pilot Study
PRP injections are safe but don't significantly improve Peyronie's Disease.
research Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
research Increased risk of telogen effluvium with tirzepatide compared to other weight-loss medications: a retrospective cohort TriNetX database study
research 5-alpha-reductase inhibitors for lower urinary tract symptoms secondary to benign prostatic obstruction
5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
research Vitamin C Deficiency-Induced Pulmonary Arterial Hypertension
Vitamin C supplementation can resolve pulmonary arterial hypertension caused by vitamin C deficiency.
research THU0189 Safety of four treatment regimens in early rheumatoid arthritis
All four treatments for early rheumatoid arthritis had similar safety profiles.
research Harmony in Healing: Investigating Platelet-Rich Plasma Activation during Acetylsalicylic Acid Treatment
Acetylsalicylic acid affects platelet-rich plasma activation, requiring personalized approaches for effective treatment.
research Mechanistic target of rapamycin (mTOR) expression is increased in acne patients' skin
Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
research PRP vs 5% topical Minoxidil: a dilemma in moderate male androgenetic alopecia
This article evaluates the effectiveness of autologous platelet-rich plasma (PRP) versus 5% topical minoxidil in treating male androgenetic alopecia (AGA), a condition affecting up to 50% of men by age 50 and linked to psychosocial burdens. The review of randomized controlled trials, systematic reviews, and clinical studies reveals that neither PRP nor minoxidil consistently outperforms the other as a standalone treatment. However, a combination therapy approach tends to yield superior outcomes for managing male AGA.
research Acneiform Rash Caused by an Unlikely Drug: Topiramate
A man got a rare rash from the drug topiramate, which went away after he stopped taking it.
research Allogeneic Hair Transplantation with Enhanced Survival by Anti-ICAM-1 Antibody with Short-Term Rapamycin Treatment in Nonhuman Primates
Using an anti-ICAM-1 antibody with rapamycin improves hair transplant survival in monkeys.
research Finasteride for recurrent priapism in children and adolescents: a report on 5 cases
Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.
research 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor
A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
research 5α‐Reductase Inhibitors
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
research Clinical and analytical evaluation of LC-MS methods for plasma renin activity and aldosterone
The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.
research Minoxidil 외용액에 의한 알레르기성 접촉피부염 1예
A man got an allergic skin reaction after using a 5% minoxidil solution for hair growth, suggesting it's important to check the ingredients of such solutions.
research Recent Advances in the Medical and Surgical Treatment of Priapism
New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.
research Alpha-blockers/finasteride: no benefit in ED
research Toxicity Test of Fixed Dose Method on Ethanol Extract of Ramania Leaves (Bouea macrophylla Griffith.) from South Kalimantan
Ramania leaf extract is non-toxic but can cause stomach ulcers at high doses.
research Influence of an iplatelant therapy with P2Y12 receptor inhibitors on platelet function in elderly patients with acute coronary syndrome
Ticagrelor works better than clopidogrel in reducing platelet activity in elderly patients with acute coronary syndrome.
research Adenoma suprarrenal productor de aldosterona
Removing an adrenal gland tumor improved a man's blood pressure and stopped his facial hair growth.
research Successful rapid subcutaneous desensitization to anakinra in a case of delayed‐type hypersensitivity reaction
A woman with a drug allergy to anakinra was successfully desensitized, allowing her to continue treatment without allergic reactions.
research Long-Term Efficacy of Ritlecitinib up to Month 24 From the ALLEGRO Phase 2b/3 and Long-Term Phase 3 Clinical Studies in Alopecia Areata
Ritlecitinib is effective for long-term treatment of severe alopecia areata.
research COMPARISON OF PLATELET RICH THERAPY ALONE WITH PLATELET RICH THERAPY ALONG WITH DAILY TOPICAL 5% PROCAPIL APPLICATION FOR THE TREATMENT OF ANDROGENETIC ALOPECIA: A QUASI-EXPERIMENTAL CLINICAL TRIAL
Combining PRP with Procapil is more effective for hair loss treatment than PRP alone.
research Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
Finasteride may help improve certain brain function issues linked to dopamine.
research This Week in <emph>JAMA</emph>
Providing housing and case management reduces hospital visits for chronically ill homeless adults.