research The Price Waterhouse Guide to Financial Management: Tools for Improving Performance
A new method can quickly detect alcohol abuse by analyzing hair in under an hour.
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750-780 / 1000+ resultsresearch Characterization of aberrant mTOR signaling pathway in U87MG glioblastoma cell line by quantitative phosphoproteomics
Inhibiting mTORC2 can reduce DNA repair and increase cancer cell death, suggesting potential for targeted brain cancer treatments.
research Growing Up Fast: Managing Autism Spectrum Disorder and Precocious Puberty
The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.
research Adverse events related to platelet-rich plasma therapy and future issues to be resolved
PRP therapy may cause infections and other issues, needing more research for safety.
research Madarosis: A dermatological marker
research Informed consent form for platelet rich plasma injections: evidence-based and legally guide for orthopaedic surgeons
A legally valid consent form for PRP injections was created to improve communication and protect against lawsuits.
research MP44-04 TRENDS IN 5-ALPHA REDUCTASE INHIBITOR USE BEFORE AND AFTER THE FOOD AND DRUG ADMINISTRATION SAFETY WARNING
Prescriptions for 5-alpha reductase inhibitors dropped significantly after the FDA's safety warning, especially for men with benign prostatic hyperplasia.
research Pharmacovigilance in Pediatric Patients with Epilepsy Using Antiepileptic Drugs
Most children with epilepsy on antiepileptic drugs experience side effects, especially those on multiple drugs, but these drugs help reduce seizures.
research iTRAQ-based proteome profiling revealed the role of Phytochrome A in regulating primary metabolism in tomato seedling
Phytochrome A is crucial for normal metabolism and development in tomato seedlings under far-red light.
research The Growth Factors in Advanced Platelet-Rich Fibrin (A-PRF) Reduce Postoperative Complications after Mandibular Third Molar Odontectomy
A-PRF reduces pain and complications after wisdom tooth removal.
research Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes
Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
research 1. 2年間の低負荷レジスタンストレーニングが高齢者の筋機能に及ぼす効果(第134回日本体力医学会関東地方会)
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Off-label prescriptions: patient safety first
Off-label drug use can be risky and requires careful consideration to ensure patient safety.
research Effect of Platelet-Rich Plasma (PRP) on Dermal Skin Flap Survival: An Experimental Study in Rats
This experimental study on 16 female Wistar rats investigated the effects of heterologous leukocyte-rich platelet-rich plasma (L-PRP) on the viability of random-pattern dorsal skin flaps. The study found that local application of L-PRP significantly improved flap survival by reducing necrosis compared to the control group. Specifically, Group B (L-PRP treated) exhibited lower mean necrosis (0.59) and no severe necrosis cases, while Group A (control) showed higher mean necrosis (0.82) with only mediocre/severe necrosis. The results suggest that L-PRP enhances flap viability without causing adverse reactions, indicating its potential feasibility for improving skin flap outcomes.
research Rizatriptan benzoate-loaded dissolving microneedle patch for management of acute migraine therapy
Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.
research Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
research Frontotemporal dementia with parkinsonism presenting as posterior cortical atrophy
A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.
research An essential role for Rxrα in the development of Th2 responses
RXRα is crucial for proper immune response and links diet to immune function.
research Association of Trichorhinophalangeal Syndrome and Loose Anagen Syndrome: A Case Report
A family was found with both Trichorhinophalangeal syndrome and Loose Anagen Syndrome, suggesting a genetic connection.
research Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene.
Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
research 5-α-Reductase type 2 deficiency: is there a genotype-phenotype correlation? A review
No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
research Cellular retinol‐binding protein‐1 expression increases with increasing clinical severity of alopecia areata
Higher CRBP1 levels are linked to more severe alopecia areata.
research A human vitamin D receptor mutation causes rickets and impaired Th1/Th17 responses
A vitamin D receptor mutation causes rickets and affects immune responses.
research The effect of platelet rich plasma (PRP) in the hair re-growth: A randomized placebo-controlled trial
research Autologous activated platelet-rich plasma (AA-PRP) and non-activated (A-PRP) in hair growth: a retrospective, blinded, randomized evaluation in androgenetic alopecia
PRP, especially AA-PRP, can help improve hair growth in androgenetic alopecia.
research 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor
A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
research Prevention of developmental delays among children at public healthcare facilities of Pakistan: protocol for a cluster Randomized Controlled Trial
The document outlines a plan to test if certain methods can prevent developmental delays in children at Pakistani public healthcare centers.
research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Patient prioritisation of impact items to develop the patient‐reported impact of dermatological diseases (PRIDD ) measure: European Delphi data
Patients with skin diseases rated psychological effects as most impactful, needing a treatment approach that addresses both mind and body.