72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
72 citations
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September 1997 in “Dermatologic Surgery” Careful planning and patient counseling can lead to excellent hair transplant results, often in one or two sessions.
71 citations
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January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
69 citations
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August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
67 citations
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November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
66 citations
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June 2018 in “International Journal of Women's Dermatology” No cure for female pattern hair loss, but various effective treatments exist.
66 citations
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May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
66 citations
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October 2006 in “Journal of Surgical Oncology” Different scalp reconstruction methods work well, but the best one depends on the patient's unique needs.
64 citations
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July 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
62 citations
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January 2000 in “Developmental dynamics” Notch-related genes play a key role in the development and cycling of hair follicles.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
60 citations
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September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
60 citations
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March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
59 citations
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March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
58 citations
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January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
58 citations
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March 2019 in “Experimental Dermatology” Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.
57 citations
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July 2018 in “Scientific Reports” Using adipose tissue-derived fragments improves early skin graft success.
57 citations
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July 2005 in “Clinics in Plastic Surgery” Reconstruct lips with proper planning, templates, and revisions for appearance and function.
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April 2022 in “Journal of Molecular Medicine” Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
55 citations
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September 2017 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
54 citations
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January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
52 citations
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March 2016 in “JAMA dermatology” Patients with PCOS rate their hirsutism higher than clinicians, and these self-ratings are more closely related to their quality of life and risk of depression.
50 citations
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December 2020 in “Bioactive Materials” Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
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September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
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February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
48 citations
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January 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
47 citations
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February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.