research Generation and integration of hair follicle-primed spheroids in bioengineered skin constructs
Researchers made progress in creating skin with hair by integrating special cell clusters.
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870-900 / 1000+ resultsresearch Engineering Spatially Organized Hair Peg-like Structures in Human Skin Constructs Using Keratinocyte–Dermal Papilla Fibroblast Spheroids and Micropatterned Dermal Scaffolds
A method was developed to create early-stage hair structures in lab-grown skin.
research Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages
The skin can still regenerate and function well even with fewer fibroblasts.
research 577 Successful allogeneic epidermal grafting of chronic recessive dystrophic epidermolysis bullosa wounds from hematopoietic cell donors in the outpatient setting
Skin grafts from related donors significantly healed chronic wounds in patients with a severe skin condition over a year.
research Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells
Injecting specific cells into the skin can help improve skin structure and reduce blisters in a genetic skin disorder.
research A single type of progenitor cell maintains normal epidermis
One type of progenitor cell can maintain normal skin in mice.
research Hair follicle reformation induced by dermal papilla cells from human scalp skin
Dermal papilla cells can help regrow hair follicles.
research Influence of an epidermal cell extract on skin healing and scar formation.
Epidermal cell extracts improve skin healing and reduce scarring.
research Tissue-Engineered Skin Preserving the Potential of Epithelial Cells to Differentiate into Hair After Grafting
Tissue-engineered skin can support hair growth after grafting, especially with mouse-derived dermis.
research Scaffolds for epithelial and hair follicle regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research Fabrication and characterization of epithelial scaffolds for hair follicle regeneration
Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research The Formation of Vellus Hair Follicles from Human Adult Epidermis1
Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.
research Stem cells of hair follicles micrografted into a tissue-engineered dermal template (Integra®)
The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.
research Autologous smashed follicular dermal graft with epidermal cell suspension in chronic nonhealing leg ulcers
A new treatment using skin and hair cells may help heal stubborn leg ulcers effectively and safely.
research 659 Improved graft survival and hair follicle neogenesis in dermal epidermal constructs incubated with bioactive peptides
Bioactive peptides improve graft survival and new hair growth.
research Epidermal stem cells: Interplay with the skin microenvironment during wound healing
Epidermal stem cells work with the skin's environment to heal wounds effectively.
research Characterization of Hair Follicle Development in Engineered Skin Substitutes
Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human‐Induced Pluripotent Stem Cells
Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
research Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges
Skin-derived stem cells show promise for improving wound healing and creating transplantable tissue.
research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
The gene therapy showed significant wound healing and was safe for treating severe RDEB.
research In vitro mesenchymal–epithelial interaction facilitates de novo hair follicle formation
Adult skin cells can be used to create new hair in a lab.
research Epidermal stem cells: skin surveillance and clinical perspective
Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
research 1250 Development of an ex vivo human skin explant model to examine candidate gene functions in the hair follicle and epidermis
The model can effectively test gene functions and drug responses in human skin.
research Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors
Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
research Programmable Artificial Skins Accomplish Antiscar Healing with Multiple Appendage Regeneration
Artificial skin can heal wounds without scars and regenerate hair, oil, and sweat glands.
research Plasticity of Epithelial Cells during Skin Wound Healing
Epithelial cells adapt and work together to heal skin wounds effectively.
research Successful Treatment of Chronic Leg Ulcers with Epidermal Equivalents Generated from Cultured Autologous Outer Root Sheath Cells
Using patient's own hair cells can effectively heal chronic leg ulcers.
research Bioengineering strategies for regeneration of skin integrity: A literature review
Stem cells and new methods can help heal and regenerate damaged skin.
research Template for Skin Regeneration
The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.