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A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Pill organizers and cutters can help with taking medication regularly but may affect the medication's effectiveness and safety.

Certain gut bacteria can lower androgen levels in male mice.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

5α-reductase inhibitors lower overall prostate cancer risk but not high-grade cancer risk; longer-term screening and new treatments show promise.

Proretinal nanoparticles improve skin absorption and reduce irritation of topical retinoids.

Hypospadiac rats showed abnormal genital development, useful for studying human hypospadias.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

5α-reductase inhibitors may lower the risk of death from bladder cancer.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Early intervention for acute urinary retention can reduce costs and improve care.

Gender-affirming hormone therapy and surgery affect gut bacteria differently.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Taking dutasteride every other day works as well as daily and better preserves sexual function.

Goserelin injections can effectively manage hyperandrogenism symptoms in postmenopausal women who can't have surgery.

Early use of infliximab in severe pediatric Crohn's disease can lead to significant improvement and remission.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Topical finasteride may be safer than oral finasteride, but more research is needed.

Metyrapone effectively stabilizes severe Cushing's disease symptoms before surgery.

Carpronium chloride increases blood flow by widening small blood vessels.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Treatment for benign prostatic hyperplasia involves drugs that either quickly relieve symptoms or reduce prostate size, with a combination offering more benefits but more side effects.

CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.

Severe digestive issues in DRESS need early endoscopy for better treatment.

Adherence to finasteride treatment for prostate issues is generally low.

GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.