June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
August 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Stem cell therapies show potential for treating hair loss with fewer side effects.
August 2015 in “PubMed Central” Epithelial-derived Pop-Up Keratinocytes (ePUKs) may enhance wound healing in regenerative medicine.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
3 citations
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July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Zebrafish regenerate sensory hair cells through three phases, offering insights for potential mammal applications.
23 citations
,
November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
2 citations
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November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
2 citations
,
August 2012 in “Cell Stem Cell” The study showed that some hair follicle stem cells wake up to grow hair while others stay asleep, and that the environment around them is important for hair growth.
1201 citations
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January 2010 in “Science” Active and quiescent stem cells work together in mammals to maintain and repair tissues.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
92 citations
,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
45 citations
,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
28 citations
,
January 1997 in “Elsevier eBooks” Keratinocyte stem cells help regenerate and repair cornea, skin, and hair.
20 citations
,
January 2014 in “Tissue and Cell” MEBO ointment helps activate and grow skin stem cells for burn healing.
17 citations
,
December 2014 in “Cell Stem Cell” Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
9 citations
,
January 2016 in “International Journal of Medical Sciences” Increasing Wnt10b levels can help grow new hair follicles in mice.
4 citations
,
January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.
4 citations
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May 2015 in “Macedonian Veterinary Review” Canine stem cell aggregates can effectively replace natural dermal papillae for hair research.
4 citations
,
January 2011 in “Cell stem cell” Hair follicle stem cells can return to their original niche and help regenerate hair.
3 citations
,
December 2013 in “Journal of Cell Science” Keratin 79 cells help form and regenerate hair canals.
2 citations
,
September 2024 in “Biomedical Research and Therapy” MSCs should be called "master signaling cells" because they mainly help with cell communication and tissue repair.
1 citations
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February 2024 in “Journal of Microscopy and Ultrastructure” Exosomes from stem cells speed up wound healing.
May 2026 in “Frontiers in Cell and Developmental Biology” Mesenchymal stem cells and their vesicles show promise for burn treatment but face challenges in standardization and clinical application.
November 2025 in “Journal of Investigative Dermatology” Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.
September 2024 in “British journal of surgery” Autologous stem cell therapy may effectively increase hair density in Androgenetic Alopecia.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Elf5 is important for skin stem cell growth and could help treat skin and hair problems.