November 2012 in “Transplantation” Large corneum layer cells can cover wounds effectively.
Equine hoof progenitor cells can help develop therapies for hoof diseases like laminitis.
January 2016 in “eScholarship (California Digital Library)” HBCs in the olfactory epithelium can self-renew or differentiate into other cell types, with specific patterns during regeneration.
46 citations
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December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
4 citations
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May 2009 in “Wound Repair and Regeneration” Genetically modified cells can regenerate skin and hair in rats.
1 citations
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April 2012 in “Cancer Research” Antizyme reduces tumor growth and normalizes skin cell development affected by MEK.
5 citations
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April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The gene therapy showed significant wound healing and was safe for treating severe RDEB.
1 citations
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May 2024 in “Journal of Dermatological Science” Injecting specific cells into the skin can help improve skin structure and reduce blisters in a genetic skin disorder.
July 2024 in “Journal of Investigative Dermatology” Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.
10 citations
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March 2016 in “Development Growth & Differentiation” Scientists created feather buds in lab-grown chick skin using specific cell interactions.
March 2026 in “Frontiers in Bioengineering and Biotechnology” Stem cell-derived fibroblasts can effectively repair skin wounds.
9 citations
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July 2008 in “Oncology Reports” HPV16-transformed cells can change human skin cell properties, aiding tumor growth.
July 2019 in “Tumor Biology” Bone marrow-derived cells contribute to skin tumors, suggesting new treatment targets for non-melanoma skin cancers.
39 citations
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September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
10 citations
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May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
315 citations
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June 2001 in “Nature Genetics” 14 citations
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May 2008 in “Journal of Visualized Experiments” Mouse epidermal neural crest stem cells can become various cell types and are easily obtained from hair follicles.
28 citations
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January 2009 in “Journal of Investigative Dermatology” Stem cells in eccrine glands could be used for regenerative medicine.
46 citations
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July 2015 in “Wound repair and regeneration” Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.
23 citations
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November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
December 2004 in “PLoS ONE” The Foxn1(-/-) phenotype disrupts hair growth and affects skin stem cells.
10 citations
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January 2019 in “International Immunology” Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
10 citations
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December 2015 in “International Journal of Molecular Sciences” PDCD4 is important for controlling skin cell growth and healing.
5 citations
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September 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
9 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Human melanocytes have unique traits that affect melanoma development and prognosis.
August 2013 in “International Wound Journal” Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
73 citations
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April 2013 in “Stem cells” LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
April 2021 in “Journal of Investigative Dermatology” Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
39 citations
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January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.