21 citations
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January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
Surgical repigmentation can permanently restore color to white hair in vitiligo patients.
September 2018 in “CRC Press eBooks” Hair and nail disorders can cause changes in scalp pigmentation, especially with sun exposure and alopecia.
February 2026 in “Journal of Cutaneous and Aesthetic Surgery” Ectopic acanthosis nigricans can occur at surgical sites due to skin graft mismatches.
August 2018 in “Journal of The American Academy of Dermatology” A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.
7 citations
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January 2013 in “Indian dermatology online journal” A rare skin condition with dark, thick, warty patches and some hair loss was found in a newborn boy.
November 2024 in “Karnataka Pediatric Journal” Chikungunya can cause hyperpigmentation in children and should be considered in diagnosis.
1 citations
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January 2008 in “SKINmed Dermatology for the Clinician” Treatment with prednisolone and dapsone stopped new blisters and partially healed previous ones.
10 citations
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August 1998 in “Journal of Investigative Dermatology” 16 citations
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February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
15 citations
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July 2004 in “AIDS” Indinavir therapy can cause reversible skin, hair, and nail darkening.
9 citations
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September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.
December 2025 in “Dermatology Reports” Topical ruxolitinib quickly improves non-segmental vitiligo.
7 citations
,
March 2003 in “PubMed” The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
Isotretinoin effectively improved severe pityriasis rubra pilaris with complications.
A rare skin condition in a 17-year-old was diagnosed late, stressing the need for careful evaluation and genetic testing.
June 2025 in “British Journal of Dermatology” Melanocytic matricoma can look like skin cancer but is usually harmless; surgery and follow-up are advised.
3 citations
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March 2021 in “Cureus” A rare combination of halo nevi, nonsegmental vitiligo, and early gray hair can occur together.
82 citations
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November 1985 in “Archives of Dermatology” The newborn's skin condition improved over time, leaving only lighter skin patches.
January 2022 in “Skin appendage disorders” A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.
June 2023 in “Pediatric investigation” A boy's scalp infection, usually found on the body, was effectively treated with antifungal cream.
32 citations
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May 2023 in “Preprints.org” Skin pigmentation varies due to genetics, UV exposure, and medications, with treatments available but requiring medical advice.
August 2021 in “Indian dermatology online journal” A young boy with a rare skin and nail condition improved significantly with simple topical treatments.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” A 73-year-old woman with Hypopigmented Mycosis Fungoides, a rare skin lymphoma, experienced disease progression despite treatment, emphasizing the need for ongoing monitoring.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
4 citations
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October 2019 in “Skin Appendage Disorders” Gefitinib can cause hair and eyebrow darkening.
12 citations
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January 2021 in “Dermatology Research and Practice” The 1927 nm Thulium laser effectively and safely treats postinflammatory hyperpigmentation in darker skin tones.
2 citations
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June 2018 in “Dermatologic Surgery” 19 citations
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November 1985 in “Archives of Dermatology” The newborn's skin blisters healed without scarring, leaving some light spots, and stopped forming after four months.
11 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.