September 2025 in “Frontiers in Cell and Developmental Biology” Retinoic acid may help heal skin without scars by reducing fibrosis and supporting skin regeneration.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
437 citations
,
August 2014 in “Cell metabolism” Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
253 citations
,
March 2006 in “The Journal of Clinical Endocrinology and Metabolism” Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.
222 citations
,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
165 citations
,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
70 citations
,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
65 citations
,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
62 citations
,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
53 citations
,
June 2012 in “Annales d'Endocrinologie” The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
47 citations
,
June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
41 citations
,
June 2016 in “Reviews in endocrine and metabolic disorders” Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.
40 citations
,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
40 citations
,
July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
35 citations
,
May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
32 citations
,
July 2018 in “Scientific Reports” Essential-oils-cobalt improves goat growth and product quality.
31 citations
,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
31 citations
,
January 1981 in “Pharmacology & Therapeutics” Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
27 citations
,
August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found new genes involved in hair growth, which could help develop new hair treatments.
15 citations
,
February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
14 citations
,
October 2020 in “Natural Products and Bioprospecting” Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
14 citations
,
October 2019 in “International Journal of Women's Health” Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.
14 citations
,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
13 citations
,
October 2010 in “Pharmacogenomics” Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
8 citations
,
May 2017 in “Current traditional medicine” Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.
7 citations
,
June 2021 in “Trends in Food Science and Technology” Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
7 citations
,
July 2007 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” The medication lopinavir-ritonavir may cause severe hair loss.