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Did you mean Reverse Transcription Polymerase Chain Reaction?

GlossaryReverse Transcription Polymerase Chain Reaction

method to convert RNA into DNA and amplify it

Reverse Transcription Polymerase Chain Reaction (RT-PCR) is a laboratory technique used to convert RNA into DNA and then amplify specific DNA sequences. This method is crucial for studying gene expression, detecting RNA viruses, and diagnosing diseases, as it allows scientists to measure the amount of RNA in a sample by first transcribing it into complementary DNA (cDNA) and then amplifying it for analysis.

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research Molecular mapping of lymph node metastases by real-time reverse transcription polymerase chain reaction in two melanoma patients

March 2011 in “Journal of Dermatology”

The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.

research Analysis of LncRNA and mRNA Expression Profiles in Skin Tissues of Super Merino Sheep and Small-Tailed Han Sheep

November 2023

Researchers found genes in sheep that may affect hair growth and wool quality.

research Expression analysis of KAP9.2 and Hoxc13 genes during different cashmere growth stages by qRT-PCR method

9 citations , June 2014 in “Molecular biology reports”

KAP9.2 and Hoxc13 genes are important for cashmere growth and vary in activity during different stages.

research Identification and profiling of microRNA between back and belly Skin in Rex rabbits (Oryctolagus cuniculus)

1 citations , June 2018 in “World rabbit science”

Different miRNAs in Rex rabbit skin affect cell processes and hair growth.

research Skin-specific transgenic overexpression of ovine β-catenin in mice

2 citations , January 2023 in “Frontiers in Genetics”

Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.

research URTICA DIOICA EXTRACT DOWNREGULATES THE GENE EXPRESSION OF 5Α-RII IN HACAT CELLS: POSSIBLE IMPLICATIONS AGAINST ANDROGENIC SKIN DISEASES.

1 citations , January 2023 in “PubMed”

Urtica dioica extract may help treat androgenic skin diseases by reducing a specific gene's activity.

Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction

research Analysis of Gene Expression in Isolated Single Hair Follicles: An Approach Using Semiquantitative Reverse-Transcriptase—Polymerase Chain Reaction

May 1995 in “Journal of Investigative Dermatology”

Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.

research Clinical picture, diagnosis, treatment and outcome of severe acute respiratory syndrome (SARS) in children

42 citations , November 2004 in “Paediatric Respiratory Reviews”

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

research Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene.

24 citations , July 1994 in “Molecular Endocrinology”

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

research Extraction and Detection of mRNA from Horsehair

5 citations , January 2006 in “Journal of veterinary medical science”

RNA can be extracted from horsehair roots for analysis.

research Analysis of gene expression patterns and levels in maize hybrids and their parents

5 citations , January 2015 in “Genetics and Molecular Research”

Maize hybrids show better early growth due to complex gene interactions from their parent strains.

EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

research EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes

12 citations , December 2020 in “Archives animal breeding/Archiv für Tierzucht”

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

Researchers found WNT10A to be a key gene in developing goat hair follicles.

research Association Between Human Hair Loss and the Expression Levels of Nucleolin, Nucleophosmin, andUBTFGenes

5 citations , February 2016 in “Genetic Testing and Molecular Biomarkers”

Hair loss is significantly linked to lower levels of certain genes in hair follicles.

research Polymorphism in the A2M gene associated with high-quality milk in Murrah buffaloes (Bubalus bubalis)

5 citations , January 2016 in “Genetics and molecular research”

Certain genetic variations in the A2M gene are linked to better milk quality in Murrah buffaloes.

research Characterization and expression analysis of KAP7.1, KAP8.2 gene in Liaoning new-breeding cashmere goat hair follicle

48 citations , February 2010 in “Molecular biology reports”

KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.

Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss Side Effect

research Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss-Side Effect

15 citations , February 2019 in “Journal of clinical medicine”

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

Phloroglucinol Enhances Anagen Signaling and Alleviates H2O2-Induced Oxidative Stress in Human Dermal Papilla Cells

research Phloroglucinol Enhances Anagen Signaling and Alleviates H₂O₂-Induced Oxidative Stress in Human Dermal Papilla Cells

March 2024 in “Journal of Microbiology and Biotechnology”

Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.

research Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

242 citations , February 2016 in “Science”

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations

research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

21 citations , November 2022 in “Frontiers in immunology”

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Red Ginseng Extract Promotes Hair Growth in Cultured Human Hair Follicles

research Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

49 citations , November 2014 in “Journal of Medicinal Food”

Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.

research Quantitative Single-Cell Approaches to Stem Cell Research

106 citations , November 2014 in “Cell Stem Cell”

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease

research Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease

11 citations , January 2000 in “Journal of Cutaneous Pathology”

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing

research Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing

32 citations , March 2014 in “PLOS ONE”

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

research Cutaneous wound healing: canine allogeneic ASC therapy

20 citations , June 2020 in “Stem Cell Research & Therapy”

Using stem cells from fat tissue can significantly improve wound healing in dogs.

research Oestrogen functions in skin and skin appendages

68 citations , June 2005 in “Expert Opinion on Therapeutic Targets”

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

To Identify the Expression of Intracellular Toll-Like Receptors in Peripheral Blood Mononuclear Cells of Alopecia Areata

research TO IDENTIFY THE EXPRESSION OF INTRACELLULAR TOLL-LIKE RECEPTORS (TLRS) IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF ALOPECIA AREATA

November 2023

Alopecia areata patients have higher levels of certain immune receptors, suggesting new treatment possibilities.

research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer

28 citations , January 2012 in “Biological & pharmaceutical bulletin”

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

research Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection

December 2025 in “Nature Communications”

Skin organoids can model tuberculosis infection and help test treatments.

research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes

5 citations , October 2020 in “Frontiers in Cell and Developmental Biology”

Reducing FOXA2 in skin cells lowers their ability to grow hair.