January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
29 citations
,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
168 citations
,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
98 citations
,
August 2007 in “PLoS ONE” Myc changes chromatin in stem cells, causing them to leave their niche.
12 citations
,
May 2013 in “International Journal of Molecular Sciences” Stem cells from elderly skin can become neurons, offering potential for brain therapy.
1 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
November 2022 in “Journal of Investigative Dermatology” Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.
January 2006 in “Chinese Journal of Dermatology” Mesenchymal cells are essential for hair follicle stem cell growth.
37 citations
,
July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
2 citations
,
September 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicle niches are specified before they form and depend on progenitor cells.
January 2016 in “Methods in molecular biology” HAP stem cells in hair follicles could help repair nerves and spinal cords.
17 citations
,
May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
3 citations
,
July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
22 citations
,
October 2007 in “Journal of Investigative Dermatology” Stem cells in mouse nails are found in the nail matrix and may control nail growth.
17 citations
,
December 2013 in “PLoS ONE” The postnatal thymus has cells like mesenchymal stem cells that can become different cell types and help maintain thymus structure.
3 citations
,
December 2024 in “Stem Cell Reports” Low fucosylation boosts stem cell growth in the eye.
1201 citations
,
January 2010 in “Science” Active and quiescent stem cells work together in mammals to maintain and repair tissues.
14 citations
,
January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
13 citations
,
July 2020 in “Stem Cell Research & Therapy” Young donor, early passage stem cells have the highest stemness.
11 citations
,
May 2018 in “Philosophical Transactions of the Royal Society B” New materials help control stem cell growth and specialization for medical applications.
12 citations
,
October 2024 in “Cell”
34 citations
,
April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
16 citations
,
July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
6 citations
,
November 2023 in “JCI Insight” Exogenous stem cells can effectively integrate into hair follicles, promoting hair growth.
6 citations
,
March 2011 in “European Journal of Dermatology” Nestin-positive cells are important for hair follicle regeneration in alopecia areata.
Extracellular matrix components affect stem cell growth and adhesion differently based on their source.
1 citations
,
January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
218 citations
,
April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.