research Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia
Natural killer and CD8+ T cells play a key role in hair loss in androgenetic alopecia.
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research Inhibition of the Hippo pathway by verteporfin reduces the proliferation and stemness of rat hair follicle neural crest stem cells under hypoxia
Verteporfin reduces growth and stem cell traits in rat hair follicle cells by blocking the Hippo pathway.
research Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Exosomes derived from mouse vibrissa dermal papilla cells promote hair follicle regeneration during wound healing by activating Wnt/β-catenin signaling pathway
Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.
research Piperine reduces hair oiliness by inhibiting adipogenesis of hair stem cells
Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
research A guide to the use of bioassays in exploration of natural resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Status of research on the development and regeneration of hair follicles
New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
research Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration
3D-printed membranes with smart sensors can greatly improve tissue healing and have many medical applications.
research In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research A volar skin excisional wound model for in situ evaluation of multiple-appendage regeneration and innervation
The study concluded that the new wound model can be used to evaluate skin regeneration and nerve growth.
research ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth
ISX9 helps regrow hair by activating a specific cell signaling pathway.
research miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network
miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
research Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death
Cedrol may be an effective treatment for colorectal cancer.
research Exosomal miRNA-218–5p derived from low-passage dermal papilla cells modulates hair follicle growth and development
Exosomal miRNA-218-5p promotes hair growth and development.
research Drug Repositioning: New Approaches and Future Prospects for Life-Debilitating Diseases and the COVID-19 Pandemic Outbreak
Drug repositioning offers a cost-effective, lower-risk way to treat diseases and pandemics like COVID-19.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research Chemical Composition of Different Hair Types
research Optimizing treatment management of trastuzumab deruxtecan in clinical practice of breast cancer
Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.
research A review of the ethnomedicinal, antimicrobial, and phytochemical properties of Musa paradisiaca (plantain)
Plantain has potential medicinal benefits but needs more research for safety and effectiveness.
research A review on computer‐aided chemogenomics and drug repositioning for rationalCOVID ‐19 drug discovery
Computer-aided methods can speed up COVID-19 drug discovery and help find new uses for existing drugs.
research Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa
Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
research The Role of Sex and Gender in Dermatology - From Pathogenesis to Clinical Implications
Understanding sex and gender differences can improve personalized dermatology care.
research Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation
New skin repair methods show promise but need to be safer and more accessible.
research Unveiling the Potential of Single‐Cell Encapsulation in Biomedical Applications: Current Advances and Future Perspectives
Single-cell encapsulation shows promise for medical use but faces production challenges.
research Bubble-Based Drug Delivery Systems: Next-Generation Diagnosis to Therapy
Bubble-based systems show promise for precise, targeted drug delivery and diagnosis, especially in cancer treatment.
research Foxn1 in Skin Development, Homeostasis and Wound Healing
Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
research International PCOS guideline clinical research priorities roadmap: a co-designed approach aligned with end-user priorities in a neglected women’s health condition
The roadmap calls for better research and funding to improve PCOS diagnosis, treatment, and health outcomes.
research Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid
Fusidic acid can be an effective topical treatment for superficial bacterial infections in dogs.
research Effect of Adiantum Capillus veneris Linn on an Animal Model of Testosterone-Induced Hair Loss.
Adiantum capillus-veneris Linn reduced hair loss and improved hair growth in mice with testosterone-induced alopecia.