July 2025 in “Burns & Trauma” 3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
60 citations
,
February 2014 in “Tissue Engineering Part A” Microporous scaffolds speed up skin healing and regeneration.
January 2025 in “SSRN Electronic Journal”
162 citations
,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
102 citations
,
April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
1 citations
,
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.
23 citations
,
May 2024 in “Bioactive Materials” Biomimetic biomaterials can improve skin healing by mimicking natural tissue and reducing immune rejection.
The conclusion is that closing scalp wounds is possible, but restoring hair without donor material is still a major challenge.
23 citations
,
September 2018 in “Journal of Investigative Dermatology” A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
9 citations
,
January 1995 in “Aesthetic Plastic Surgery” New suturing technique with wider intervals and shallow stitches helps prevent scalp scars and promotes hair growth.
23 citations
,
November 2018 in “npj Regenerative Medicine” Healing of heart and skin wounds in animals are similar.
18 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” Controlling immune responses with biomaterials can reduce scarring and improve skin regeneration.
66 citations
,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
1 citations
,
December 2015 in “Dermatologic Surgery” Double trichophytic closure effectively treats thin scalp scars and reduces patient costs.
April 2023 in “Journal of Investigative Dermatology” Covering a wound can stop hair growth by promoting scarring, but boosting a process called Wnt signaling can help hair grow back even when the wound is covered.
1 citations
,
August 2023 in “International Journal of Surgery Case Reports” Using titanium mesh and thigh tissue is effective for complex scalp reconstruction.
28 citations
,
June 2020 in “ACS Biomaterials Science & Engineering” The new ECM patch greatly improves wound healing and tissue regeneration.
August 2004 in “Journal of the American College of Surgeons” Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
1 citations
,
July 2025 in “The Open Dermatology Journal” Tissue engineering in cosmetics offers safer, more effective products and ethical alternatives to animal testing.
75 citations
,
January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
February 2008 in “Medical & surgical dermatology” Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.
March 2006 in “The FASEB Journal” Two methods improved nerve regeneration and touch recovery in skin grafts for burn patients.
28 citations
,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
42 citations
,
April 2016 in “Plastic and reconstructive surgery/PSEF CD journals” The hydrogel with fractionated PRP improves skin regeneration by enhancing wound healing and growth of skin structures.
14 citations
,
January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
October 2021 in “Austin journal of biomedical engineering” The material combining eggshell protein and scaffold helps wounds heal faster and regenerates tissue effectively.
November 2019 in “SLAS technology” New findings suggest certain genes and microRNAs are crucial for wound healing, and innovative technologies like smart bandages and apps show promise in improving treatment.
December 2015 in “Dermatologic Surgery” Double trichophytic closure effectively repairs thin scalp scars, reducing financial burden.
Wound healing involves three phases and various cells and factors, with scars typically forming in adults. Chronic wounds can occur due to various issues, and abnormal scarring can lead to hypertrophic or keloid scars. Emerging research areas include the role of proteins, microRNAs, macrophage manipulation, and stem cell treatment.
December 2024 in “Regenerative Therapy” Stem cells and new methods can help heal and regenerate damaged skin.