research Preparation and Evaluation of Curcumin Nanocrystals for Topical Administration: Cell Line Analysis and Histopathological Examination
Curcumin nanocrystal gel improves skin absorption and is safe and effective for topical use.
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research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Wedelolactone, a natural coumestan with multiple pharmacological effects
Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
research The multifaceted regulatory effect of icariin on macrophages: a mini-review
Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.
research Valproic acid boosts hair follicle stem cell resilience to oxygen-glucose deprivation through autophagy induction and AKT/mTOR suppression
Valproic acid helps hair follicle stem cells survive better in low oxygen and glucose conditions.
research Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury
Blocking autophagy worsens lipid buildup and dysfunction in brain cells after injury.
research EARLY CARDIAC DAMAGE FOLLOWING SINGLE AND COMBINED EXPOSURE TO LITHIUM CARBONATE AND LEAD ACETATE IN RATS: A TOXICOLOGICAL PERSPECTIVE
Lithium carbonate and lead acetate together harm the heart more than individually.
research Leveraging Crosslinker Diffusion to Template Stiffness Gradients in Alginate Hydrogels
Stiffness gradients in alginate gels can guide cancer cell invasion and study cellular behaviors.
research Activation of the integrated stress response in human hair follicles
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
research Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis
Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.
research Enhancement of drug permeation across skin through stratum corneum ablation
Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.
research Development of novel wound dressing based on elastin-like recombinamers for skin regeneration
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
research Polymorphisms of OCT1 and metformin effects in Iraqi women with polycystic ovary syndrome in Karbala city
Hormone levels can help predict metformin treatment success in women with PCOS.
research Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research mTOR signaling in hair follicle and hair diseases: recent progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research Avaliação de respostas defensivas associadas ao pânico em ratas: perfil da ativação serotonérgica no núcleo dorsal da rafe e substância cinzenta periaquedutal
Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.
research The Role of Vimentin in Tissue Repair and Cell Growth
Vimentin is crucial for wound healing, cell growth, and managing immune responses.
research Hair loss after covid 19 - case series
COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
research NEW CHALLENGE TO CANCER AND LONGEVITY
A group has developed therapies that show promise for treating cancer and various other conditions.
research Cryogelation of human hair keratins
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
research Present Chemotherapy Induced Alopecia and Research in Future
Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.
research The story of when kidneys fail and the contribution of Air Vice-Marshal Sir Ralph Jackson
Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.
research Tackling underrepresentation to aid understanding of Parkinson’s disease: Progress and further opportunities
Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol
Early NAS level changes affect alcohol consumption vulnerability.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research Unravelling the link between insulin resistance and androgen excess
AKR1C3 could be a treatment target for metabolic issues in PCOS.