126 citations
,
November 1987 in “The Journal of Pediatrics” Selenium deficiency can cause skin and hair color loss, muscle weakness, and blood cell changes, but these improve with selenium supplements.
115 citations
,
December 1996 in “PubMed” The safe daily selenium intake is up to 819 micrograms.
93 citations
,
March 2014 in “Cochrane Database of Systematic Reviews” The review updated previous findings on selenium's role in cancer prevention, analyzing 55 observational studies with over 1,100,000 participants and 8 RCTs with 44,743 participants. Observational studies suggested a lower cancer incidence and mortality with higher selenium exposure, particularly for stomach, bladder, and prostate cancers, but these results were limited by study design and quality. RCTs showed no clear evidence that selenium supplementation reduced cancer risk or mortality, with some trials indicating potential harmful effects, such as increased risk of type 2 diabetes, alopecia, and dermatitis. Overall, no convincing evidence supported selenium supplements as a preventive measure against cancer in humans.
79 citations
,
April 1996 in “JAMA” Taking too many selenium supplements can cause serious health problems like hair loss and fatigue.
76 citations
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April 2002 in “Urology” Selenium and vitamin E supplements have mixed effects on prostate cancer risk and may not be beneficial for everyone.
71 citations
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June 2008 in “Annals of Internal Medicine” Excessive selenium from supplements can be harmful.
61 citations
,
May 2010 in “Integrative Cancer Therapies” There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
55 citations
,
February 1990 in “Journal of Nutrition” Selenium in hair and nails is higher with L-selenomethionine and low methionine.
35 citations
,
January 2001 in “Journal of Animal Science” High dietary selenium, especially inorganic, causes weight loss and selenosis in pigs, with effects varying by hair color.
35 citations
,
April 1956 in “Journal of the American Medical Association” Selenium sulfide shampoo can cause hair loss, which stops when you stop using it.
30 citations
,
September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
27 citations
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June 2010 in “Journal of the American Academy of Dermatology” Excessive selenium in supplements can cause hair loss and nail issues.
23 citations
,
October 1995 in “PubMed” Selenium exposure at work caused the worker's complete hair loss.
23 citations
,
August 1989 in “American Journal of Veterinary Research” High selenium diets in pigs cause health issues like weight loss, hair loss, and nerve damage.
21 citations
,
June 1991 in “Journal of Inherited Metabolic Disease” Selenium deficiency caused symptoms in a child, which improved with selenium supplements.
20 citations
,
February 2013 in “Nutrition” Selenium-enriched green tea might be a safe prebiotic for gut health.
20 citations
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August 1960 in “PubMed” Selenium sulfide may affect hair root health.
16 citations
,
May 2019 in “Hormone and Metabolic Research” Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.
16 citations
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December 2005 in “Journal of Animal Physiology and Animal Nutrition” Moderate selenium levels in a dog's diet are best for hair growth.
16 citations
,
January 1996 Selenium levels in Enshi District need careful monitoring to prevent health issues.
15 citations
,
July 1984 in “Nutrition Research” Selenium increased in hair but not in blood after taking supplements.
15 citations
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March 1997 in “International Journal of Dermatology” Selenium sulfide in anti-dandruff shampoos can turn hair green.
12 citations
,
July 1964 in “Archives of Dermatology” Selenium sulfide shampoo doesn't affect hair growth or rest phases.
11 citations
,
January 2016 in “BMC veterinary research” Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.
9 citations
,
September 1989 in “PubMed” Sudanese children with severe malnutrition have low selenium levels, which may affect their recovery.
7 citations
,
March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
6 citations
,
March 2011 in “Experimental Dermatology” Too much or too little selenium in the diet can cause hair loss and graying in mice.
5 citations
,
July 2019 in “Nutrients” Low selenium intake may delay puberty in boys but not in girls.
4 citations
,
January 1989 Hair and nails can indicate selenium levels in the body.
4 citations
,
January 2016 in “Dermatology online journal” Using bacitracin zinc and selenium sulfide one after the other can temporarily turn white hair yellow.