research Systemic subchronic toxicity and comparison of four selenium nutritional supplements by 90-day oral exposure in Sprague-Dawley rats
High doses of some selenium supplements caused liver and reproductive harm in rats.
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research Three-Dimensional Analysis of Sex- and Gonadal Status- Dependent Microglial Activation in a Mouse Model of Parkinson’s Disease
Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
research Selenium and its Inorganic Compounds [BAT Value Documentation, 2011]
Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.
research The Nutrient–Skin Connection: Diagnosing Eating Disorders Through Dermatologic Signs
Skin, hair, and nail changes can help detect eating disorders early.
research Repurposing of Various Current Medicines as Radioprotective Agents
Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.
research Some Trace Elements' Level in Alopecia Areata
Alopecia areata patients have lower zinc, copper, and selenium levels than healthy people.
research Descriptive analysis of whole blood concentrations of toxic, essential, and trace elements in adult females from the MIREC-ENDO study
Most women had adequate essential elements except zinc, and lead levels were higher in peri-/post-menopausal women.
research Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia
Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.
research Alterations in transcriptome and antioxidant activity of naturally aged mice exposed to selenium-rich rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research Evidence- and consensus-based recommendations for the use of pegvaliase in adults with phenylketonuria
Pegvaliase is recommended for treating adults with phenylketonuria.
research Prostate cancer prevention
Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
research Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation
Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
research Nano drug delivery systems: a promising approach to scar prevention and treatment
Nanotechnology could improve scar treatment but needs more development.
research Shortcutting the diagnostic odyssey: the multidisciplinary Program for Undiagnosed Rare Diseases in adults (UD-PrOZA)
The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.
research Two cases of low-prostate-specific antigen localized prostate cancer incidentally detected by computed tomography
CT scans can find serious prostate cancer even when PSA levels are low.
research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research Alert to US physicians: DHEA, widely used as an OTC androgen supplement, may exacerbate COVID-19
The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.
research Repurposing Auranofin for Oncology and Beyond: A Brief Overview of Clinical Trials as Mono- and Combination Therapy
Auranofin shows promise as a cancer treatment, especially when combined with other therapies.
research New Selenoderivatives as Antitumoral Agents
Selenium shows promise in preventing and controlling prostate cancer.
research 4-hydroxynonenal, a lipid peroxidation product, inhibits glutathione peroxidase: Protective effect of glutathione
Selenium is crucial for health, but both deficiency and excess can cause problems.
research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle
research Sodium selenate as a disease-modifying treatment for mild–moderate Alzheimer’s disease: an open-label extension study
Sodium selenate was found to be safe and possibly slows Alzheimer's progression, but more research is needed.
research Selenium Toxicity: A Case of Selenosis Caused by a Nutritional Supplement
Excessive selenium from supplements can be harmful.
research [The value of selenotherapy in patients with mucoviscidosis].
Selenium therapy improved health in cystic fibrosis patients with fewer side effects at a lower dose.
research CLINICAL AND HAEMATOLOGICAL STUDIES ON EXPERIMENTALLY INDUCED SELENOSIS IN CROSSBRED COW CALVES
Selenosis in calves causes health issues and changes in blood parameters.
research Clinical and haematological studies on experimentally induced selenosis in crossbred cow calves.
Selenosis in calves causes health issues and changes in blood parameters.
research Selenium In Thioredoxin Reductase: Resistance To Oxidative Inactivation, Oxidation States, And Reversibility Of Chemical Reactions
Selenium in proteins helps prevent over-oxidation and supports chemical reversibility.
research The relationship of hair color to selenium content of hair and selenosis in swine
research CosmeticPotential of a Structural Protein CopolymerBased on Silk, Elastin, and Keratin
SELP::KP improves hair strength, elasticity, and health, making it a promising hair cosmetic.
research SELENIUN1M BLOOD AND HAIR OF HEALTH PERSON FROM NPC HIGH AND LOW RISK AREA OF GUANGDONG PROVINCE
Selenium levels are similar in healthy people from both high and low NPC risk areas.