Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.
July 2024 in “Journal of Investigative Dermatology” Substance P helps restore skin thickness and cell renewal when sensory nerves are reduced.
34 citations
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July 2006 in “The Journal of Comparative Neurology” Increasing neurotrophin 4 in skin boosts nerve endings but not sensory neuron count.
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
1 citations
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January 2001 in “PubMed” Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
A new imaging method helps see and study touch nerve endings in mouse skin.
1 citations
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November 2024 in “eLife” Mesenchymal MEIS2 is essential for whisker development without needing sensory nerves.
Meis2 is essential for whisker development, independent of nerve involvement.
October 2014 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” A new type of nerve cell involved in itch perception was discovered.
28 citations
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March 2011 in “Journal of Investigative Dermatology” Hair follicles help guide nerve growth, improving touch recovery in skin grafts.
2 citations
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April 2014 in “PubMed” Epidermal neural crest stem cells from hair follicles can help repair nerve injuries.
71 citations
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
March 2006 in “The FASEB Journal” Two methods improved nerve regeneration and touch recovery in skin grafts for burn patients.
34 citations
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November 1991 in “Choice Reviews Online” Neurons and synapses are key to brain function and learning.
1 citations
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October 2015 in “OakTrust (Texas A&M University Libraries)” Harp seals have different innervation patterns in their whiskers, with lateral whiskers having more axons than medial ones.
1 citations
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September 2017 in “BMJ” The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.
March 2025 in “Frontiers in Cell and Developmental Biology” Improving nerve and immune interactions may help heal chronic wounds.
31 citations
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November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
122 citations
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June 1998 in “PubMed” Neurotrophins regulate nerve growth by balancing promotion and suppression.
5 citations
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August 2005 in “Anatomy and Embryology” Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.
January 2024 in “Archives of pharmacy practice” The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
2 citations
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June 2025 in “International Journal of Nanomedicine” New biomaterials can improve wound healing by promoting nerve and tissue regeneration.
19 citations
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February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
8 citations
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June 2025 in “Stem Cell Research & Therapy” Exosome therapy may help treat diabetic nerve damage, but more research is needed.
January 2025 in “Nature Communications” Large-scale reconstructions enhance understanding of vibrissal sensory mapping in the brain.
January 2022 in “Exclusive Real World Evidence Journal” A rare form of lupus can cause severe nerve damage and other symptoms, but treatment can help.
June 2007 in “Emergency medicine news” If someone has unexplained nerve pain and hair loss, doctors should check for thallium poisoning.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
CRPS I is complex, linked to immune and nerve issues, and needs comprehensive treatment.