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Exploring the Therapeutic Potential of Selaginella Doederleinii Extract for Cervical Cancer Treatment Through Network Pharmacology and In Vitro Studies

research Exploring the therapeutic potential of Selaginella doederleinii extract for cervical cancer treatment through network pharmacology and in vitro studies

January 2026 in “Journal of Applied Pharmaceutical Science”

Selaginella doederleinii extract shows potential for cervical cancer treatment but needs more research.

research c-Kit - The Novel Receptor: Physiological Roles, Downstream Signaling and Implications in Cancer

4 citations , January 2021 in “Journal of Clinical Medical Research”

c-Kit is important for heart regeneration and cancer development.

research Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development

22 citations , August 1999 in “Mechanisms of Development”

Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.

research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man

109 citations , November 2011 in “Nature Neuroscience”

research Hyperadrenocorticism in Ferrets

6 citations , January 2013

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats

40 citations , June 2013 in “Scientific Reports”

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

research Phosphatidylinositol‐specific phospholipase C2 functions in auxin‐modulated root development

28 citations , December 2018 in “Plant, cell & environment/Plant, cell and environment”

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

research Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids

26 citations , March 2006 in “Endocrine, metabolic & immune disorders. Drug targets”

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

research Incomplete Sjögren-Larsson Syndrome in Two Japanese Siblings?

1 citations , January 1999 in “Dermatology”

research Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids

13 citations , January 2015 in “Steroids”

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice

81 citations , February 2014 in “EMBO molecular medicine”

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

research A novel mutation in the connexin 26 gene (GJB2) in a child with clinical and histological features of keratitis–ichthyosis–deafness (KID) syndrome

34 citations , September 2010 in “Clinical and Experimental Dermatology”

A new gene mutation linked to KID syndrome was found, expanding genetic knowledge.

research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)

May 2010 in “Europe PMC (PubMed Central)”

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

research The contribution of corneodesmosin to androgenetic alopecia

September 2003 in “American Journal of Human Genetics”

research Androgen receptor-mediated gene activation in prostate cancer cells

1 citations , September 2010 in “UEF eRepo (University of Eastern Finland)”

Androgen receptors help prostate cancer cells grow and resist drugs.

research Chromosomal localization of acidic and basic keratin genes of the domestic dog

9 citations , April 1999 in “Mammalian Genome”

Acidic keratin genes are on CFA9 and basic keratin genes are on CFA27 in dogs.

research Epidermal Differentiation Enhances CRABP II Expression in Human Skin

21 citations , December 1994 in “Journal of Investigative Dermatology”

research GJB6 missense variant in a Labrador Retriever with paw pad hyperkeratosis

January 2026 in “Animal Genetics”

A genetic variant in the GJB6 gene likely caused the Labrador's paw pad condition.

research Granulocyte colony stimulating factor promotes scarless tissue regeneration

4 citations , September 2024 in “Cell Reports”

Granulocyte colony stimulating factor helps heal wounds without scars.

research Structure of human type II 5 alpha-reductase gene

76 citations , September 1992 in “Endocrinology”

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

research Identification of two additional novel mutations in the AR gene associated with severe forms of androgen insensitivity syndrome

1 citations , September 2019 in “Steroids”

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

research Decision letter: Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata

April 2018

Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.

research Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells

April 2025 in “Journal of the Association for Research in Otolaryngology”

NM2 and RLC phosphorylation are essential for normal inner ear hair cell function.

research Mutation of the doublecortin gene in male patients with double cortex syndrome: Somatic mosaicism detected by hair root analysis

43 citations , September 2001 in “Annals of Neurology”

Hair root analysis can effectively detect somatic mosaicism in double cortex syndrome.

research Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2

35 citations , January 2006 in “Cancer Research”

Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.

OsUEV1B, a Ubc Enzyme Variant Protein, Is Required for Phosphate Homeostasis in Rice

research OsUEV1B, an Ubc enzyme variant protein, is required for phosphate homeostasis in rice

4 citations , February 2021 in “Plant journal”

OsUEV1B protein is essential for controlling phosphate levels in rice.

research Spiking dependence of SARS‐CoV‐2 pathogenicity on TMPRSS2

30 citations , February 2021 in “Journal of Medical Virology”

TMPRSS2 affects COVID-19 severity and treatment options.

research Evolution, classification, structure, and functional diversification of steroid 5α-reductase family in eukaryotes

6 citations , July 2024 in “Heliyon”

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

research Identification of functional circRNAs regulating ovarian follicle development in goats

8 citations , September 2024 in “BMC Genomics”

circCFAP20DC helps goat ovarian cells grow, aiding follicle development.

research Towards the Development of AgoKirs: New Pharmacological Activators to Study Kir2.x Channel and Target Cardiac Disease

9 citations , August 2020 in “International Journal of Molecular Sciences”

New compounds may help treat heart disease by activating specific potassium channels.

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