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research Anti-androgenic potential of the fruit extracts of certain Egyptian Sabal species and their genetic variability studies: a metabolomic-molecular modeling approach

1 citations , January 2022 in “Food & Function”

Certain Egyptian Sabal fruit extracts may help treat anti-androgenic diseases like benign prostatic hyperplasia.

Post Finasteride Syndrome: Demographics from FDA Database

research 054 Post Finasteride Syndrome: Guess Who-Demographics from FDA Database

April 2016 in “The Journal of Sexual Medicine”

Younger people (median age 35) experience more PFS-like symptoms with 1mg finasteride; more research needed.

research Protective effects of melatonin against metabolic and reproductive disturbances in polycystic ovary syndrome in rats

41 citations , September 2014 in “Journal of Pharmacy and Pharmacology”

Melatonin may help treat PCOS symptoms in rats.

research Involvement of neurosteroids in the control of prolactin secretion in sheep under basal, stressful and pregnancy conditions

August 2022 in “Theriogenology”

Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.

research 697 Prostaglandin D2-enhanced testosterone metabolism in human keratinocytes is mediated by reactive oxygen species

1 citations , April 2016 in “Journal of Investigative Dermatology”

Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.

research Endocrine Aspects of Female Sexual Dysfunction

100 citations , July 2004 in “The Journal of Sexual Medicine”

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

6 citations , September 2015 in “Journal of Medicinal Chemistry”

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

research Selective non-steroidal inhibitors of 5α-reductase type 1

49 citations , January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

research Finasteride

June 2021 in “Reactions Weekly”

Finasteride caused serious side effects and led to six suicides.

research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances

153 citations , November 2004 in “Current Medicinal Chemistry”

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

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